User profiles for L. Thorpe

Lorna Thorpe

- Verified email at nyulangone.org - Cited by 10876

Lilian Thorpe

- Verified email at usask.ca - Cited by 3180

PI3K in cancer: divergent roles of isoforms, modes of activation and therapeutic targeting

LM Thorpe, H Yuzugullu, JJ Zhao - Nature Reviews Cancer, 2015 - nature.com
Phosphatidylinositol 3-kinases (PI3Ks) are crucial coordinators of intracellular signalling in
response to extracellular stimuli. Hyperactivation of PI3K signalling cascades is one of the …

Health effects with consumption of the flax lignan secoisolariciresinol diglucoside

…, SJ Whiting, BHJ Juurlink, LU Thorpe… - British Journal of …, 2010 - cambridge.org
Flaxseed is the richest source of the lignan secoisolariciresinol diglucoside (SDG). After
ingestion, SDG is converted to secoisolariciresinol, which is further metabolised to the …

[HTML][HTML] An overview of 9/11 experiences and respiratory and mental health conditions among World Trade Center Health Registry enrollees

…, S Galea, D Williamson, TR Frieden, L Thorpe - Journal of Urban …, 2008 - Springer
To date, health effects of exposure to the September 11, 2001 disaster in New York City
have been studied in specific groups, but no studies have estimated its impact across the …

Differences in PTSD prevalence and associated risk factors among World Trade Center disaster rescue and recovery workers

…, L DiGrande, K Wheeler, L Thorpe… - American Journal of …, 2007 - Am Psychiatric Assoc
Objective: This study compared the prevalence and risk factors of current probable posttraumatic
stress disorder (PTSD) across different occupations involved in rescue/recovery work at …

Risk of hepatitis C virus infection among young adult injection drug users who share injection equipment

LE Thorpe, LJ Ouellet, R Hershow… - American journal of …, 2002 - academic.oup.com
Designing studies to examine hepatitis C virus (HCV) transmission via the shared use of drug
injection paraphernalia other than syringes is difficult because of saturation levels of HCV …

The Met Office global coupled model 3.0 and 3.1 (GC3. 0 and GC3. 1) configurations

…, R Schiemann, D Storkey, L Thorpe… - Journal of Advances …, 2018 - Wiley Online Library
The Global Coupled 3 (GC3) configuration of the Met Office Unified Model is presented. Among
other applications, GC3 is the basis of the United Kingdom's submission to the Coupled …

Infants' perception of melodies: The role of melodic contour

SE Trehub, D Bull, LA Thorpe - Child development, 1984 - JSTOR
Infants 8-11 months of age were exposed to repetitions of a 6-tone sequence or melody, then
tested for their discrimination of transpositions of that sequence as well as other melodic …

Speaking the same language: treatment outcome definitions for multidrug-resistant tuberculosis

KF Laserson, LE Thorpe, V Leimane… - … of Tuberculosis and …, 2005 - ingentaconnect.com
SETTING: Globally it is estimated that 273000 new cases of multidrug-resistant tuberculosis
(MDR-TB, resistance to isoniazid and rifampicin) occurred in 2000. To address MDR-TB …

[HTML][HTML] Gut microbiome dysbiosis in antibiotic-treated COVID-19 patients is associated with microbial translocation and bacteremia

…, G Putzel, A Pironti, E Wilder, LE Thorpe… - Nature …, 2022 - nature.com
Although microbial populations in the gut microbiome are associated with COVID-19 severity,
a causal impact on patient health has not been established. Here we provide evidence …

Assessment of community-level disparities in coronavirus disease 2019 (COVID-19) infections and deaths in large US metropolitan areas

…, JM Feldman, O Ogedegbe, L Thorpe… - JAMA network …, 2020 - jamanetwork.com
Urban counties in large metropolitan areas in the United States are among the most affected
by the coronavirus disease 2019 (COVID-19) pandemic, with high proportions of confirmed …