The present clinical trial investigated the impact of selected SNPs in CES1 on the metabolic
activity of the enzyme. For this purpose, we used methylphenidate (MPH) as a …

… Tarang Sharma,1 ,2 Louise Schow Guski,1 ,2 Nanna Freund,1 ,2 Peter C Gøtzsche1 ,2 … 48
Larun L, Nordheim LV, Ekeland E, Hagen KB, Heian F. Exercise in prevention and treatment …

… Emma Maund and Louise Schow Guski contributed to the acquisition of data. All of the
authors contributed to the analysis and interpretation of data and to the drafting and revising of …

… Independent reviews are more reliable than those undertaken by the industry, which are
four times more likely to show positive effects for their own drug, when compared to …

Aims This study investigated the influence of CES1 variations, including the single
nucleotide polymorphism (SNP) rs71647871 (G143E) and variation in copy number, on the …

… However, as we were unable to show any metabolic differences between the groups with
two and three copies of CES1, we chose not to stratify the CES1A1c group and the 143E allele …

… The results of the study show that total noise annoyance is strongly determined by the
average sound pressure level L pAeq,24h of the “most annoying” noise source (in this case …

Background: This paper describes a systematic review and meta-analyses on effects of
environmental noise on annoyance. The noise sources include aircraft, road, and rail …

… Raw & Griffrths [ 1 l] show that Mean Annoyance (the mean of raw annoyance scores) may
be significantly changed by level changes in the order of 3 dB(A), and the effect of changes …

… The results show an overall increase in correct localizations with a sound-reflecting
surface on the floor. Especially the elevation of the sound source can be detected with greater …