User profiles for L. LaBine

Lisa Labine

University of Toronto
Verified email at mail.utoronto.ca
Cited by 108

The use of nuclear magnetic resonance (NMR) and mass spectrometry (MS)–based metabolomics in environmental exposure assessment

LM Labine, MJ Simpson - Current opinion in environmental science & …, 2020 - Elsevier
The environment has many anthropogenic chemicals which, in sublethal concentrations, can
alter the biochemical function of organisms. Environmental metabolomics uses analytical …

Environmental metabolomics uncovers oxidative stress, amino acid dysregulation, and energy impairment in Daphnia magna with exposure to industrial effluents

LM Labine, EAO Pereira, S Kleywegt, KJ Jobst… - Environmental …, 2023 - Elsevier
… The water hardness was approximately 120 mg/L (CaCO 3 ), consistent with municipal tap
… water and supplemented with 1 μg/L of each selenium and cobalamin to optimize health and …

Comparison of sub-lethal metabolic perturbations of select legacy and novel perfluorinated alkyl substances (PFAS) in Daphnia magna

LM Labine, EAO Pereira, S Kleywegt, KJ Jobst… - Environmental …, 2022 - Elsevier
… /L) and high (15 mg/L) concentrations of mixtures containing equal concentrations of PFOS,
PFOA, and GenX were used, representing total PFAS concentrations of 3 mg/L and 45 mg/L

Daphnia magna sub-lethal exposure to phthalate pollutants elicits disruptions in amino acid and energy metabolism

EAO Pereira, LM Labine, S Kleywegt, KJ Jobst… - Aquatic Toxicology, 2023 - Elsevier
… ranging in the low mg/L suggests that a pattern of physical … magna in the range of µg/L
to mg/L reported a reduction in … in the range of µg/L to mg/L and their degradation products …

Closing the gap in postfracture care at the population level: a randomized controlled trial

WD Leslie, L LaBine, P Klassen, D Dreilich… - CMAJ, 2012 - Can Med Assoc
Background: Postfracture care is suboptimal, and strategies to address this major gap in
care are necessary. We investigated whether notifications sent by mail to physicians and …

[HTML][HTML] Metabolomics Reveals That Bisphenol Pollutants Impair Protein Synthesis-Related Pathways in Daphnia magna

EA Oliveira Pereira, LM Labine, S Kleywegt, KJ Jobst… - Metabolites, 2021 - mdpi.com
… /L, is twice as lethal as BPF (LC 50 = 42.890 mg/LL, can immobilize the freshwater species
at lower concentrations in comparison with BPF (EC 50 = 56 mg/L) and BPS (EC 50 = 55 mg/L

[HTML][HTML] Characterizing the use of virtual care in primary care settings during the COVID-19 pandemic: a retrospective cohort study

A Singer, L Kosowan, L LaBine, D Shenoda, A Katz… - BMC Primary …, 2022 - Springer
Background In March 2020, Canada implemented restrictions to curb viral transmission of
COVID-19, which resulted in abrupt disruptions to conventional (in-person) clinical care. To …

Metabolomics revealed disruptions in amino acid and antioxidant biochemistry in Daphnia magna exposed to industrial effluents associated with plastic and polymer …

EAO Pereira, LM Labine, S Kleywegt, KJ Jobst… - Environmental …, 2024 - Elsevier
Industrial wastewater effluents are a major source of chemicals in aquatic environments, and
many of these chemicals may negatively impact aquatic life. In this study, the crustacean …

Metabolomic analysis predicted changes in growth rate in Daphnia magna exposed to acetaminophen

E Lari, TY Jeong, LM Labine, MJ Simpson - Aquatic Toxicology, 2022 - Elsevier
… magna was calculated to be 3.61 mg/L (95 % confidence intervals: 2.68 and 4.79 mg/L).
Exposure concentrations for sub-lethal acute exposure experiments were selected at 10% and 1…

Patient values and preferences on Polypharmacy and Deprescribing: a Scoping review

…, D McMillan, R Linthorst, L Kosowan, L Labine… - International Journal of …, 2021 - Springer
Background Understanding how patient values and preferences towards polypharmacy and
deprescribing have been studied is important to gain insight on current knowledge in this …