Diclofenac is a frequently prescribed nonsteroidal antiinflammatory drug (NSAID). Significant
hepatotoxicity related to diclofenac may be more common than previously recognized, as …

Ursodeoxycholic acid, a dihydroxyl bile acid normally present in human beings in minimal
amounts, becomes incorporated into the bile salt pool when taken orally. In cholestasis, bile …

Abstract Treatment of patients with primary biliary cirrhosis (PBC) using ursodeoxycholic
acid (UDCA) leads to a reduction in serum bilirubin. The first objective of this study was to …

In a randomized controlled trial, 41 chronic hepatitis B virus carriers were allocated, by
opening numbered computerized randomization envelopes, to receive recombinant interferon‐…

Studies of the mechanism of elimination of infected hepatocytes during the course of acute
type B hepatitis suggest that early in the infection, interferon is produced which stimulates an …

Background: Autoimmune hepatitis is an immunologically mediated disorder with some
similarities to systemic lupus erythematosus, including an association with HLA-A1, B8, DR3. …

Punthakee Z, Scully LJ, Guindi MM, Ooi TC (Department of Medicine, Division of
Gastroenterology, Department of Pathology and the Laboratory of Medicine and the Division of …

In order to understand the mechanisms underlying the development of chronic hepatitis B
virus (HBV) infection and to develop methods of treatment, we must first understand how the …

Continuing hepatitis B virus (HBV) infection is normally associated with the presence of
hepatitis B surface antigen (HBsAg) in the serum. In spite of sensitive screening assays for …

Urticaria has been described only rarely in patients with hepatitis A virus infection, although
its association with acute hepatitis B virus infection is well recognized. A young male …