User profiles for Kimberly Skead
 | Kimberly SkeadOntario Institute for Cancer Research Verified email at oicr.on.ca Cited by 214 |
[HTML][HTML] Gene-by-environment interactions in urban populations modulate risk phenotypes
…, V Bruat, JC Grenier, E Gbeha, K Skead… - Nature …, 2018 - nature.com
Uncovering the interaction between genomes and the environment is a principal challenge
of modern genomics and preventive medicine. While theoretical models are well defined, …
of modern genomics and preventive medicine. While theoretical models are well defined, …
The politics of universal health coverage
The UN has declared universal health coverage an urgent global goal. Efforts to achieve
this goal have been supported by rigorous research on the scientific, technical, and …
this goal have been supported by rigorous research on the scientific, technical, and …
Cohort profile: the Ontario health study (OHS)
VA Kirsh, K Skead, K McDonald… - International journal …, 2023 - academic.oup.com
Mandated recruitment goals were surpassed, and both the OHS and CanPath are the largest
volunteer cohort studies ever conducted in Canada. The collection of baseline data, core …
volunteer cohort studies ever conducted in Canada. The collection of baseline data, core …
The evolution of SARS-CoV-2 seroprevalence in Canada: a time-series study, 2020–2023
Background: During the first year of the COVID-19 pandemic, the proportion of reported
cases of COVID-19 among Canadians was under 6%. Although high vaccine coverage was …
cases of COVID-19 among Canadians was under 6%. Although high vaccine coverage was …
[HTML][HTML] Provincial variation in colorectal cancer screening adherence in Canada; evidence from the Canadian Partnership for Tomorrow's Health
Introduction Although colorectal cancer (CRC) screening program is proven to reduce CRC
incidence and mortality, understanding patterns and predictors of suboptimal adherence in …
incidence and mortality, understanding patterns and predictors of suboptimal adherence in …
[HTML][HTML] Interacting evolutionary pressures drive mutation dynamics and health outcomes in aging blood
K Skead, A Ang Houle, S Abelson, M Agbessi… - Nature …, 2021 - nature.com
Age-related clonal hematopoiesis (ARCH) is characterized by age-associated accumulation
of somatic mutations in hematopoietic stem cells (HSCs) or their pluripotent descendants. …
of somatic mutations in hematopoietic stem cells (HSCs) or their pluripotent descendants. …
[HTML][HTML] Costing universal health coverage
costs increase, among other factors. Unlike average cost, changes in marginal cost are not
linear, with significant implications. A recent report points out that overreliance on total or …
linear, with significant implications. A recent report points out that overreliance on total or …
Realizing the Educational Rights of Children with Disabilities: An Overview of Inclusive Education in Cameroon.
All children deserve access to education, including those in low income countries. Educators
and teachers share a desire to promote inclusive education, and can came together, such …
and teachers share a desire to promote inclusive education, and can came together, such …
Pre-diagnosis plasma cell-free DNA methylome profiling up to seven years prior to clinical detection reveals early signatures of breast cancer
Profiling of cell-free DNA (cfDNA) has been well demonstrated to be a potential non-invasive
screening tool for early cancer detection. However, limited studies have investigated the …
screening tool for early cancer detection. However, limited studies have investigated the …
Early signatures of breast cancer up to seven years prior to clinical diagnosis in plasma cell-free DNA methylomes
Limited studies to date have investigated the detectability of cell-free DNA (cfDNA) markers
in asymptomatic individuals prior to a cancer diagnosis. Here, we performed cfDNA …
in asymptomatic individuals prior to a cancer diagnosis. Here, we performed cfDNA …
