Carboxyhemoglobin half-life in carbon monoxide-poisoned patients treated with 100% oxygen at atmospheric pressure

LK Weaver, S Howe, R Hopkins, KJ Chan - Chest, 2000 - Elsevier
Study objectives There are large reported differences for the carboxyhemoglobin (COHb)
half-life (COHb t 1/2 ) in humans breathing 100% atmospheric O 2 following CO inhalation in …

[HTML][HTML] The impact of the tumor microenvironment on macrophage polarization in cancer metastatic progression

…, MMH Yung, HYS Ngan, KKL Chan, DW Chan - International journal of …, 2021 - mdpi.com
Rather than primary solid tumors, metastasis is one of the hallmarks of most cancer deaths.
Metastasis is a multistage event in which cancer cells escape from the primary tumor survive …

[HTML][HTML] Molecular biomarkers for the early detection of ovarian cancer

R Zhang, MKY Siu, HYS Ngan, KKL Chan - International Journal of …, 2022 - mdpi.com
Ovarian cancer is the deadliest gynecological cancer, leading to over 152,000 deaths each
year. A late diagnosis is the primary factor causing a poor prognosis of ovarian cancer and …

Cross‐cultural adaptation and validation of the Chinese Voice Handicap Index‐10

PKY Lam, KM Chan, WK Ho, E Kwong… - The …, 2006 - Wiley Online Library
Objectives/Hypothesis: Recent developments in voice assessment propose the use of quality
of life measurements. The Voice Handicap Index (VHI) is one of the most psychometrically …

[HTML][HTML] Hyperbaric oxygen for acute carbon monoxide poisoning

LK Weaver, RO Hopkins, KJ Chan… - … England Journal of …, 2002 - Mass Medical Soc
Background Patients with acute carbon monoxide poisoning commonly have cognitive
sequelae. We conducted a double-blind, randomized trial to evaluate the effect of hyperbaric-…

Two-year cognitive, emotional, and quality-of-life outcomes in acute respiratory distress syndrome

…, D Collingridge, RB Parkinson, KJ Chan… - American journal of …, 2005 - atsjournals.org
Acute respiratory distress syndrome (ARDS) has a high mortality and is associated with
significant morbidity. Prior outcome studies have focused predominant on short-term outcomes (6…

Peanuts as a source of β-sitosterol, a sterol with anticancer properties

AB Awad, KC Chan, AC Downie, CS Fink - Nutrition and Cancer, 2000 - Taylor & Francis
Work from our laboratory, as well as others, suggests a protective role of phytosterols (PS),
especially β-sitosterol, from colon, prostate, and breast cancer. Asians and vegetarians …

The effect of anchors and training on the reliability of perceptual voice evaluation

KMK Chan, EML Yiu - 2002 - ASHA
Perceptual voice evaluation is a common clinical tool for rating the severity of vocal quality
impairment. However, the evaluation process involves subjective judgment, and reliability is …

Loss of MKP3 mediated by oxidative stress enhances tumorigenicity and chemoresistance of ovarian cancer cells

DW Chan, VWS Liu, GSW Tsao, KM Yao… - …, 2008 - academic.oup.com
The RAS-RAF-MEK-extracellular signal-regulated kinase (ERK) pathway plays a pivotal role
in various cellular responses, including cellular growth, differentiation, survival and motility. …

Pulmonary function and health-related quality of life in survivors of acute respiratory distress syndrome

…, RO Hopkins, D Pope, KJ Chan… - American journal of …, 2003 - atsjournals.org
Although survival rates for acute respiratory distress syndrome have increased, there is only
limited information regarding the quality of life and the relationship between quality of life …