User profiles for K. Doucette

Karen Doucette

University of Alberta
Verified email at ualberta.ca
Cited by 3911

[HTML][HTML] Recent drug approvals for acute myeloid leukemia

C Lai, K Doucette, K Norsworthy - Journal of hematology & oncology, 2019 - Springer
Acute myeloid leukemia (AML) is the most common form of acute leukemia in adults, with an
incidence that increases with age, and a generally poor prognosis. The disease is clinically …

Pneumocystis jirovecii: a review with a focus on prevention and treatment

RB Weyant, D Kabbani, K Doucette, C Lau… - Expert opinion on …, 2021 - Taylor & Francis
Introduction: Pneumocystis jirovecii (PJ) is an opportunistic fungal pathogen that can cause
severe pneumonia in immunocompromised hosts. Risk factors for Pneumocystis jirovecii …

Selective speciation improves efficacy and lowers toxicity of platinum anticancer and vanadium antidiabetic drugs

KA Doucette, KN Hassell, DC Crans - Journal of Inorganic Biochemistry, 2016 - Elsevier
Improving efficacy and lowering resistance to metal-based drugs can be addressed by
consideration of the coordination complex speciation and key reactions important to vanadium …

Efficacy of antiretroviral therapy programs in resource-poor settings: a meta-analysis of the published literature

LC Ivers, D Kendrick, K Doucette - Clinical Infectious Diseases, 2005 - academic.oup.com
Background . Despite the advent of effective combination antiretroviral drug therapy (ART)
for the treatment of human immunodeficiency virus (HIV) infection, many doubt the feasibility …

Nontuberculous mycobacterial infection in hematopoietic stem cell and solid organ transplant recipients

K Doucette, JA Fishman - Clinical infectious diseases, 2004 - academic.oup.com
Nontuberculous mycobacteria (NTM) are ubiquitous environmental organisms. In immunocompetent
hosts, they are a rare cause of disease. In immunocompromised hosts, disease due …

[HTML][HTML] Solid organ transplantation from hepatitis B virus–positive donors: consensus guidelines for recipient management

…, A Pillai, KE Doucette, J Levitsky, MI Morris, K Lu… - American Journal of …, 2015 - Elsevier
Use of organs from donors testing positive for hepatitis B virus (HBV) may safely expand the
donor pool. The American Society of Transplantation convened a multidisciplinary expert …

Management of chronic hepatitis C: consensus guidelines

M Sherman, S Shafran, K Burak, K Doucette… - Canadian Journal of …, 2007 - hindawi.com
Since the last consensus conference on the management of chronic viral hepatitis, a number
of studies looking at modifications of the standard course of treatment have been published…

A prospective molecular surveillance study evaluating the clinical impact of community-acquired respiratory viruses in lung transplant recipients

…, S Studer, D Pakstis, K McCurry, K Doucette… - …, 2010 - journals.lww.com
Background. Community-acquired respiratory viral infections (RVIs) are common in lung
transplant patients and may be associated with acute rejection and bronchiolitis obliterans …

Occult hepatitis B virus infection in a North American community-based population

…, S Caouette, LE Nicolle, A Gutkin, K Doucette… - Journal of …, 2005 - Elsevier
BACKGROUND/AIMS: Occult hepatitis B virus (HBV) infection [HBV-DNA detection in hepatitis
B surface antigen (HBsAg)-negative individuals] may cause acute and/or chronic liver …

[HTML][HTML] Beta cell extracellular vesicle miR-21-5p cargo is increased in response to inflammatory cytokines and serves as a biomarker of type 1 diabetes

AJ Lakhter, RE Pratt, RE Moore, KK Doucette, BF Maier… - Diabetologia, 2018 - Springer
Aims/hypothesis Improved biomarkers are acutely needed for the detection of developing
type 1 diabetes, prior to critical loss of beta cell mass. We previously demonstrated that …