The activity and stability of the p53 tumor suppressor are regulated by the human homologue
of the mouse double minute 2 (Hdm2) oncoprotein. It has been hypothesized that small …

Background: Choline, an essential nutrient, is required for cell membranes, lipoprotein
secretion, and methyl-group metabolism. Recently, it has been proposed that excess dietary …

… Kevin Leonard follows this verbal" battle for Los Angeles" immediately before, during, and
after the war. Until late 1942 few people challenged the idea that" race" determined how a …

Cationic chalcogenopyrylium dyes 2−4 were synthesized in six steps from 4-(dimethylamino)phenylethyne
(7), have absorption maxima in methanol of 594, 631, and 672 nm, …

Choline is a precursor to phosphatidylcholine (PC), a structural molecule in cellular
membranes that is crucial for cell growth and function. PC is also required for the secretion of …

Background & Aims Dysregulation of liver lipid metabolism is associated with the development
and progression of nonalcoholic fatty liver disease, a spectrum of liver diseases including …

Cationic chalcogenopyrylium dyes 5 were synthesized in six steps from p-aminophenylacetylene
(9), have absorption maxima in methanol of 623, 654, and 680 nm for thio-, seleno-, …

De novo phosphatidylcholine (PC) synthesis via CTP:phosphocholine cytidylyltransferase-α
(CTα) is required for VLDL secretion. To determine the precise role of de novo PC synthesis …

Objective: The current study sought to investigate whether experiential avoidance (EA)
mediates the effect of shame on posttraumatic symptoms (PTS) in a population of trauma-…

A series of thiopyrylium (2), selenopyrylium (3), and telluropyrylium dyes (4) was prepared
via the addition of Grignard reagents to either 2,6-di(4-dimethylamino)phenylchalcogenopyran…