Global patterns of opioid use and dependence: harms to populations, interventions, and future action

…, M Hickman, P Vickerman, BDL Marshall, J Bruneau… - The Lancet, 2019 - thelancet.com
We summarise the evidence for medicinal uses of opioids, harms related to the extramedical
use of, and dependence on, these drugs, and a wide range of interventions used to …

High rates of HIV infection among injection drug users participating in needle exchange programs in Montreal: results of a cohort study

J Bruneau, F Lamothe, E Franco… - American Journal of …, 1997 - academic.oup.com
Needle exchange programs (NEPs) are designed to prevent human immunodeficiency
virus (HIV) transmission among injection drug users. Although most studies report beneficial …

Sofosbuvir and velpatasvir for hepatitis C virus infection in people with recent injection drug use (SIMPLIFY): an open-label, single-arm, phase 4, multicentre trial

…, B Hajarizadeh, J Amin, J Bruneau… - The lancet …, 2018 - thelancet.com
Background Despite revised guidelines that no longer exclude people who inject drugs (PWID)
from treatment for hepatitis C virus (HCV) infection, many clinicians are reluctant to treat …

Programmed death-1–induced interleukin-10 production by monocytes impairs CD4+ T cell activation during HIV infection

…, J Van Grevenynghe, MR Boulassel, J Bruneau… - Nature medicine, 2010 - nature.com
Viral replication and microbial translocation from the gut to the blood during HIV infection
lead to hyperimmune activation, which contributes to the decline in CD4 + T cell numbers …

Evidence of innate lymphoid cell redundancy in humans

…, M Petit, N Yessaad, F Touzot, J Bruneau… - Nature …, 2016 - nature.com
Innate lymphoid cells (ILCs) have potent immunological functions in experimental conditions
in mice, but their contributions to immunity in natural conditions in humans have remained …

[HTML][HTML] Management of opioid use disorders: a national clinical practice guideline

J Bruneau, K Ahamad, MÈ Goyer, G Poulin, P Selby… - Cmaj, 2018 - Can Med Assoc
Julie Bruneau reports monetary compensation as advisor from Gilead and Merck, outside
of … Julie Bruneau and Evan Wood wrote the first version of the manuscript. All authors were …

Hepatitis C elimination among people who inject drugs: challenges and recommendations for action within a health systems framework

E Day, M Hellard, C Treloar, J Bruneau… - Liver …, 2019 - Wiley Online Library
The burden of hepatitis C infection is considerable among people who inject drugs ( PWID ),
with an estimated prevalence of 39%, representing an estimated 6.1 million people who …

High rates of forward transmission events after acute/early HIV-1 infection

…, R Thomas, D Rouleau, J Bruneau… - The Journal of …, 2007 - academic.oup.com
Background. A population-based phylogenetic approach was used to characterize human
immunodeficiency virus (HIV)—transmission dynamics in Quebec. Methods. HIV-1 pol …

Understanding polydrug use: review of heroin and cocaine co‐use

F Leri, J Bruneau, J Stewart - Addiction, 2003 - Wiley Online Library
The use of cocaine by heroin‐dependent individuals, or by patients in methadone or
buprenorphine maintenance treatment, is substantial and has negative consequences on health, …

Opiate substitution treatment and HIV transmission in people who inject drugs: systematic review and meta-analysis

…, S Minozzi, N Martin, P Vickerman, S Deren, J Bruneau… - Bmj, 2012 - bmj.com
… research scientist5, Julie Bruneau professor6, Louisa Degenhardt professor and NHMRC
senior research fellow7 8, Matthew Hickman professor in public health and epidemiology1 …