Objectives: Operational definitions of cognitive impairment have varied widely in diagnosing
mild cognitive impairment (MCI). Identifying clinical subtypes of MCI has further challenged …

Objective: To determine the relation of neuritic plaques (NPs) and neurofibrillary tangles (NFTs)
to the development and evolution of Alzheimer disease (AD). Methods: An autopsy …

Sleep in the nursing home environment is extremely fragmented, possibly in part as a result
of decreased light exposure. This study examined the effect of light on sleep and circadian …

Objective: To evaluate cholinergic activity in diseases with Lewy bodies (LB; LB variant of
AD [LBV], diffuse LB disease [DLBD], and Parkinson’s disease [PD]) to determine if 1) AD …

OBJECTIVES: To examine whether treatment of obstructive sleep apnea (OSA) with continuous
positive airway pressure (CPAP) in patients with Alzheimer's disease (AD) results in …

Objective: Age at onset of diagnostic motor manifestations in Huntington disease (HD) is
strongly correlated with an expanded CAG trinucleotide repeat. The length of the normal CAG …

OBJECTIVE: To determine whether the weight loss associated with Alzheimer's disease
precedes or follows the dementia. DESIGN: Older community‐dwelling men (n = 134) and …

To determine which clinical feature(s) [among visual hallucinations (VH), extrapyramidal
signs (EPS) and visuospatial impairment] in the earliest stages of disease best predicted a …

Background: Spasticity is a common and poorly controlled symptom of multiple sclerosis.
Our objective was to determine the short-term effect of smoked cannabis on this symptom. …

Introduction: Obstructive sleep apnea (OSA) is common among patients with Alzheimer's
disease (AD). Untreated OSA exacerbates the cognitive and functional deficits. Continuous …