Long-term effect of thymectomy plus prednisone versus prednisone alone in patients with non-thymomatous myasthenia gravis: 2-year extension of the MGTX …

…, G Gelfand, S Wood, E Pringle, J Zwicker… - The Lancet …, 2019 - thelancet.com
Background The Thymectomy Trial in Non-Thymomatous Myasthenia Gravis Patients Receiving
Prednisone (MGTX) showed that thymectomy combined with prednisone was superior …

Dying of amyotrophic lateral sclerosis: Health care use and cost in the last year of life

J Zwicker, D Qureshi, R Talarico, P Bourque, M Scott… - Neurology, 2019 - AAN Enterprises
Objective To describe health care service utilization and cost for decedents with and without
amyotrophic lateral sclerosis (ALS) in the last year of life. Methods Using linked health …

Quantitative vs qualitative muscle MRI: Imaging biomarker in patients with Oculopharyngeal Muscular Dystrophy (OPMD)

…, KS Rakhra, PR Bourque, A Breiner, J Zwicker… - Neuromuscular …, 2023 - Elsevier
Oculopharyngeal muscular dystrophy (OPMD) is a genetic muscle disease causing ptosis,
severe swallowing difficulties and progressive limb weakness, although atypical …

MRI findings in a case of transient cortical blindness after cardiac catheterization

JC Zwicker, CA Sila - Catheterization and cardiovascular …, 2002 - Wiley Online Library
The magnetic resonance imaging findings in a case of transient cortical blindness (TCB) after
cardiac catheterization are described for the first time. In addition, a literature review of TCB…

Laryngospasm in amyotrophic lateral sclerosis

…, PR Bourque, J Warman‐Chardon, J Zwicker… - Muscle & …, 2022 - Wiley Online Library
Introduction Laryngospasm is an involuntary, sustained closure of sphincter musculature
that leads to an unpleasant subjective experience of dyspnea and choking. It is an …

[HTML][HTML] Palliative care at any stage of amyotrophic lateral sclerosis: a prospective feasibility study

J Zwicker, IC Smith, J Rice, R Murphy, A Breiner… - Frontiers in …, 2023 - frontiersin.org
Introduction Many patients with amyotrophic lateral sclerosis (ALS) receive palliative care (PC)
very late or not at all. The impact of PC on patients with ALS and caregivers has not been …

Novel Homozygous Variant in COQ7 in Siblings With Hereditary Motor Neuropathy

…, G Parmar, PR Bourque, A Breiner, J Zwicker… - Neurology …, 2023 - AAN Enterprises
Background and Objectives Coenzyme Q 10 (CoQ 10 ) is an important electron carrier and
antioxidant. The COQ7 enzyme catalyzes the hydroxylation of 5-demethoxyubiquinone-10 (…

[HTML][HTML] An atypical presentation of giant cell arteritis

J Zwicker, EJ Atkins, C Lum, M Sharma - CMAJ, 2011 - Can Med Assoc
Discussion The diagnosis of giant cell arteritis (also known as temporal arteritis) was not
initially considered in our patient because it was not a classic presentation. Classic features of …

Management of motor symptoms for patients with advanced Parkinson's disease without safe oral access: a scoping review

…, CL Watt, P Enright, L Sikora, J Zwicker - Journal of Palliative …, 2023 - liebertpub.com
Context: Parkinson's disease (PD) is the second most common neurodegenerative disorder
worldwide. Oral medications for control of motor symptoms are the mainstay of treatment. …

[HTML][HTML] Polio-like manifestation of Powassan virus infection with anterior horn cell involvement, Canada

…, JI Brooks, C Torres, E Pringle, J Zwicker - Emerging Infectious …, 2019 - ncbi.nlm.nih.gov
Evidence of spinal cord involvement in Powassan virus infection is largely limited to mouse
models. We report a case of a polio-like illness caused by Powassan virus infection in a 62-…