Transporter gene knockout rats are practically advantageous over murine models for
pharmacokinetic and excretion studies, but their phenotypic characterization is lacking. At present, …

Although organic anion transporting polypeptide (OATP)–mediated hepatic uptake is generally
conserved between rodents and humans at a gross pharmacokinetic level, the presence …

Although metformin hepatic distribution is critical to pharmacological activity, the drug is
cleared by urinary excretion. Metformin hepatobiliary disposition was studied in rodents …

Theoretical studies predicted that doping graphene with nitrogen can tailor its electronic
properties and chemical reactivity. However, experimental investigations are still limited …

Wearable thermoelectric devices show promise to generate electricity in a ubiquitous,
unintermittent and noiseless way for on-body applications. Three-dimensional thermoelectric …

Background The overall prognosis of oral cancer remains poor because over half of patients
are diagnosed at advanced-stages. Previously reported screening and earlier detection …

Owing to their excellent electrical properties and chemical stability, graphene field‐effect
transistors (Gr‐FET) are extensively studied for biosensing applications. However, hinging on …

Background The scoring of Ki-67 is highly relevant for the diagnosis, classification, prognosis,
and treatment in breast invasive ductal carcinoma (IDC). Traditional scoring method of Ki-…

Acute aortic dissection (AAD) is a catastrophic emergency with high mortality and misdiagnosis
rate. We aimed to determine whether circulating microRNAs allow to distinguish AAD …

Creation of functional patterns in two-dimensional (2D) materials provides opportunities to
extend their potential for applications. Transition-metal dichalcogenides (TMDCs) are suitable …