Photochromic ligands (PCLs) can be optically switched between isomers that show different
biological activities. As such, they offer an opportunity to convert ligand-actuated pathways …

Advances in synthetic chemistry, structural biology, molecular modelling and molecular
cloning have enabled the systematic functional manipulation of transmembrane proteins. By …

Methods for targeting of small molecules to cellular proteins can allow imaging with fluorophores
that are smaller, brighter, and more photostable than fluorescent proteins. Previously, …

Background and Purpose: We investigated the effect of higher therapeutic exercise doses
on walking during inpatient rehabilitation, typically commencing 1 to 4 weeks poststroke. …

This protocol describes an efficient method to site-specifically label cell-surface or purified
proteins with chemical probes in two steps: probe incorporation mediated by enzymes (PRIME…

Chemical fluorophores offer tremendous size and photophysical advantages over fluorescent
proteins but are much more challenging to target to specific cellular proteins. Here, we …

High-performance thermal insulation is a critical need for buildings. This article presents the
development and thermal characterization of composite foam insulation boards containing …

Background Individuals requiring greater physical assistance to practice walking complete
fewer steps in physical therapy during subacute stroke rehabilitation. Powered exoskeletons …

Background The ability to walk is commonly reported as a top rehabilitation priority for
individuals after a stroke. However, not all individuals with stroke are able to practice walking, …

Background Stroke Coach is a lifestyle coaching telehealth program to improve self-management
of stroke risk factors. Aims To examine the efficacy of Stroke Coach on lifestyle …