[HTML][HTML] Estrogen resistance caused by a mutation in the estrogen-receptor gene in a man
EP Smith, J Boyd, GR Frank, H Takahashi… - … England Journal of …, 1994 - Mass Medical Soc
Background and Methods Mutations in the estrogen-receptor gene have been thought to be
lethal. A 28-year-old man whose estrogen resistance was caused by a disruptive mutation in …
lethal. A 28-year-old man whose estrogen resistance was caused by a disruptive mutation in …
[HTML][HTML] Differential exoprotease activities confer tumor-specific serum peptidome patterns
…, M Fleisher, H Lilja, E Brogi, J Boyd… - The Journal of …, 2006 - Am Soc Clin Investig
Recent studies have established distinctive serum polypeptide patterns through mass
spectrometry (MS) that reportedly correlate with clinically relevant outcomes. Wider acceptance of …
spectrometry (MS) that reportedly correlate with clinically relevant outcomes. Wider acceptance of …
[HTML][HTML] Risk-Reducing Salpingo-oophorectomy in Women with a BRCA1 or BRCA2 Mutation
Background Risk-reducing salpingo-oophorectomy is often considered by carriers of BRCA
mutations who have completed childbearing. However, there are limited data supporting the …
mutations who have completed childbearing. However, there are limited data supporting the …
[PDF][PDF] A functional genomic approach identifies FAL1 as an oncogenic long noncoding RNA that associates with BMI1 and represses p21 expression in cancer
…, D Katsaros, KT Montone, JL Tanyi, Y Lu, J Boyd… - Cancer cell, 2014 - cell.com
In a genome-wide survey on somatic copy-number alterations (SCNAs) of long noncoding
RNA (lncRNA) in 2,394 tumor specimens from 12 cancer types, we found that about 21.8% of …
RNA (lncRNA) in 2,394 tumor specimens from 12 cancer types, we found that about 21.8% of …
Role of KRAS and BRAF gene mutations in mucinous ovarian carcinoma
…, O Lin, R Soslow, E Venkatraman, J Boyd - Gynecologic …, 2003 - Elsevier
OBJECTIVES: The goals of this study were to perform a comprehensive assessment of the
prevalence of KRAS oncogene mutations in invasive epithelial ovarian carcinomas of various …
prevalence of KRAS oncogene mutations in invasive epithelial ovarian carcinomas of various …
[HTML][HTML] Effect of testosterone and estradiol in a man with aromatase deficiency
…, M Faustini-Fustini, S Serpente, J Boyd… - … England Journal of …, 1997 - Mass Medical Soc
Recent reports of disruptive mutations of the genes for the estrogen receptor or for cytochrome
P-450 aromatase 1 – 6 have shed new light on the role of estrogen. In females the lack of …
P-450 aromatase 1 – 6 have shed new light on the role of estrogen. In females the lack of …
Resistance to therapy caused by intragenic deletion in BRCA2
Cells with loss of BRCA2 function are defective in homologous recombination (HR) and are
highly sensitive to inhibitors of poly(ADP-ribose) polymerase (PARP) 1 , 2 , which provides …
highly sensitive to inhibitors of poly(ADP-ribose) polymerase (PARP) 1 , 2 , which provides …
Clinicopathologic features of BRCA-linked and sporadic ovarian cancer
J Boyd, Y Sonoda, MG Federici, F Bogomolniy, E Rhei… - Jama, 2000 - jamanetwork.com
ContextMost hereditary ovarian cancers are associated with germline mutations in BRCA1
or BRCA2. Attempts to define the clinical significance of BRCA mutation status in ovarian …
or BRCA2. Attempts to define the clinical significance of BRCA mutation status in ovarian …
Accidental hypothermia
DJA Brown, H Brugger, J Boyd… - New England Journal of …, 2012 - Mass Medical Soc
Advances in rewarming have improved the prognosis for patients with hypothermia,
especially those with cardiac arrest treated with extracorporeal rewarming. This review covers …
especially those with cardiac arrest treated with extracorporeal rewarming. This review covers …
[PDF][PDF] Comprehensive genomic characterization of long non-coding RNAs across human cancers
The discovery of long non-coding RNA (lncRNA) has dramatically altered our understanding
of cancer. Here, we describe a comprehensive analysis of lncRNA alterations at …
of cancer. Here, we describe a comprehensive analysis of lncRNA alterations at …