A full-length clone coding for the rat alpha 7 nicotinic receptor subunit was isolated from an
adult brain cDNA library and expressed in Xenopus oocytes. A significant proportion of the …

The α7 subunit of the neuronal nicotinic acetylcholine receptor (nAChR) is abundantly
expressed in hippocampus and is implicated in modulating neurotransmitter release and in …

Transcripts for the β2 and the β4 nicotinic acetylcholine receptor (nAChR) subunits are found
throughout the CNS and the peripheral nervous system. These two β subunits can form …

When expressed in Xenopus oocytes, the rat α7 subunit forms homo-oligomeric nicotinic
acetylcholine receptors, which are blocked by α-bungarotoxin. Since the pharmacological and …

The α7 nicotinic acetylcholine receptor (nAChR) has been implicated in modulating neurotransmitter
release and may play a role in the regulation of neuronal growth and differentiation. …

Publisher Summary This chapter begins with the properties of receptors expressed in the
oocyte. Considerable data exist on the properties of neuronal nicotinic receptors in cells …

Acute stress increases the risk for neurodegeneration, but the molecular signals regulating
the shift from transient stress responses to progressive disease are not yet known. The “read-…

High doses of nicotine, the addictive component of tobacco, induce clonic-tonic seizures in
animals. Pharmacological and biochemical data have suggested that α7-containing neuronal …

PARTICIPATION of the neuronal nicotinic receptor subunit α6 in a physiologically relevant
receptor has yet to be demonstrated, but its high degree of expression in catecholaminergic …

The rat alpha 7 neuronal nicotinic acetylcholine receptor was expressed and studied in
Xenopus oocytes. The magnitude and reversal potential of instantaneous whole cell currents …