The proteome of human salivary fluid has the potential to open new doors for disease
biomarker discovery. A recent study to comprehensively identify and catalog the human ductal …

Electrospray ionization has enabled the establishment of a new area of ion chemistry
research based on the study of the reactions of high‐mass multiply charged ions with ions of …

Multiply-charged cations derived from electrospray of bovine ubiquitin and horse skeletal
muscle apomyoglobin have been subjected to reactions with anions derived from glow …

Recently, an approach for the “top down” sequence analysis of whole protein ions has been
developed, employing electrospray ionization, collision-induced dissociation, and ion/ion …

We estimated the genome-wide contribution of recessive coding variation in 6040 families
from the Deciphering Developmental Disorders study. The proportion of cases attributable to …

The biomedical research community at large is increasingly employing shotgun proteomics
for large-scale identification of proteins from enzymatic digests. Typically, the approach used …

Ion/ion proton transfer reactions are shown to be an effective means to facilitate the resolution
of ions in electrospray mass spectrometry that differ in mass and charge but are similar in …

Recently, we have developed a high‐resolution two‐dimensional separation strategy for the
analysis of complex peptide mixtures. This methodology employs isoelectric focusing of …

Faecal immunochemical testing (FIT) has a high sensitivity for the detection of colorectal
cancer (CRC). In a symptomatic population FIT may identify those patients who require …

VarSite is a web server mapping known disease‐associated variants from UniProt and
ClinVar, together with natural variants from gnomAD, onto protein 3D structures in the Protein …