[HTML][HTML] Potential anticancer properties of grape antioxidants
K Zhou, JJ Raffoul - Journal of oncology, 2012 - hindawi.com
Dietary intake of foods rich in antioxidant properties is suggested to be cancer protective.
Foods rich in antioxidant properties include grape (Vitis vinifera), one of the world’s largest fruit …
Foods rich in antioxidant properties include grape (Vitis vinifera), one of the world’s largest fruit …
[PDF][PDF] Prognostic and predictive value of centrally reviewed expression of estrogen and progesterone receptors in a randomized trial comparing letrozole and …
…, P Dell'Orto, BB Rasmussen, J Raffoul… - Journal of Clinical …, 2007 - researchgate.net
… J Natl Cancer Inst 97:1262-1271, 2005 11. Howell A, Cuzick J, Baum M, et al: Results of
the ATAC (Arimidex, Tamoxifen, Alone or in Combination) trial after completion of 5 years’ …
the ATAC (Arimidex, Tamoxifen, Alone or in Combination) trial after completion of 5 years’ …
[HTML][HTML] Genistein inhibits radiation-induced activation of NF-κB in prostate cancer cells promoting apoptosis and G2/M cell cycle arrest
JJ Raffoul, Y Wang, O Kucuk, JD Forman, FH Sarkar… - BMC cancer, 2006 - Springer
Background New cancer therapeutic strategies must be investigated that enhance prostate
cancer treatment while minimizing associated toxicities. We have previously shown that …
cancer treatment while minimizing associated toxicities. We have previously shown that …
Program description: a hospitalist-run, medical short-stay unit in a teaching hospital
HA Abenhaim, SR Kahn, J Raffoul, MR Becker - CMAJ, 2000 - Can Med Assoc
A HOSPITALIST-RUN MEDICAL SHORT-STAY UNIT (MSSU) was created at a university-affiliated
teaching hospital in Montreal in 1989. Its primary aim was to provide efficient and high…
teaching hospital in Montreal in 1989. Its primary aim was to provide efficient and high…
[HTML][HTML] DNA repair and cancer therapy: targeting APE1/Ref-1 using dietary agents
JJ Raffoul, AR Heydari, GG Hillman - Journal of oncology, 2012 - hindawi.com
Epidemiological studies have demonstrated the cancer protective effects of dietary agents
and other natural compounds isolated from fruits, soybeans, and vegetables on neoplasia. …
and other natural compounds isolated from fruits, soybeans, and vegetables on neoplasia. …
Caloric restriction promotes genomic stability by induction of base excision repair and reversal of its age-related decline
DC Cabelof, S Yanamadala, JJ Raffoul, ZM Guo… - DNA repair, 2003 - Elsevier
Caloric restriction is a potent experimental manipulation that extends mean and maximum
life span and delays the onset and progression of tumors in laboratory rodents. While caloric …
life span and delays the onset and progression of tumors in laboratory rodents. While caloric …
Attenuation of DNA polymerase β-dependent base excision repair and increased DMS-induced mutagenicity in aged mice
DC Cabelof, JJ Raffoul, S Yanamadala, C Ganir… - Mutation Research …, 2002 - Elsevier
The biological mechanisms responsible for aging remain poorly understood. We propose
that increases in DNA damage and mutations that occur with age result from a reduced ability …
that increases in DNA damage and mutations that occur with age result from a reduced ability …
Radiation‐induced HIF‐1α cell survival pathway is inhibited by soy isoflavones in prostate cancer cells
…, S Banerjee, D Kong, JJ Raffoul… - … journal of cancer, 2009 - Wiley Online Library
We previously showed that treatment of prostate cancer cells with soy isoflavones and
radiation resulted in greater cell killing in vitro, and caused downregulation of NF‐κB and APE1/…
radiation resulted in greater cell killing in vitro, and caused downregulation of NF‐κB and APE1/…
Down-regulation of apurinic/apyrimidinic endonuclease 1/redox factor-1 expression by soy isoflavones enhances prostate cancer radiotherapy in vitro and in vivo
JJ Raffoul, S Banerjee, V Singh-Gupta, ZE Knoll, A Fite… - Cancer research, 2007 - AACR
We previously showed that genistein, the major bioactive component of soy isoflavones,
acts as a radiosensitizer and potentiates prostate tumor cell killing by radiation in vitro and in …
acts as a radiosensitizer and potentiates prostate tumor cell killing by radiation in vitro and in …
Base excision repair deficiency caused by polymerase β haploinsufficiency: accelerated DNA damage and increased mutational response to carcinogens
DC Cabelof, ZM Guo, JJ Raffoul, RW Sobol, SH Wilson… - Cancer research, 2003 - AACR
The base excision repair pathway (BER) is believed to maintain genomic integrity by repairing
DNA damage arising spontaneously or induced by oxidizing and alkylating agents. To …
DNA damage arising spontaneously or induced by oxidizing and alkylating agents. To …