Mounting evidence has firmly established that low levels of cardiorespiratory fitness (CRF)
are associated with a high risk of cardiovascular disease, all-cause mortality, and mortality …

… levels of obesity In the two obese groups, obese women with low levels of intra-abdominal
fat had fewer metabolic alterations than obese women with visceral obesity (Despres et al., …

… Després discussed in this article has been and is currently supported by the Canadian
Institutes of Health Research (Foundation grant, FDN-167278), as well as by the Fondation of the …

The amount of abdominal visceral adipose tissue measured by computed tomography is a
critical correlate of the potentially “atherogenic” metabolic disturbances associated with …

Background Prospective studies suggest that hyperinsulinemia may be an important risk factor
for ischemic heart disease. However, it has not been determined whether plasma insulin …

Background Rimonabant, a selective cannabinoid-1 receptor (CB 1 ) blocker, has been
shown to reduce body weight and improve cardiovascular risk factors in obese patients. The …

The prevalence of obesity has increased worldwide and is a source of concern since the
negative consequences of obesity start as early as in childhood. The most commonly used …

… Dr Després has also conducted clinical studies funded by Eli Lilly Canada and by sanofi .
The author is the Scientific Director of the International Chair on Cardiometabolic Risk, which …

… The term metabolic fitness was introduced by Després et al. (52,53) to describe the state of
metabolic systems and variables predictive of the risk of diabetes and cardiovascular disease …

… Jean-Pierre Després is chair professor of human nutrition and lipidology, which is … 27
Després JP, Lamarche B. Effects of diet and physical activity on adiposity and body fat distribution: …