… J. Marill was supported by a studentship from ARC (Villejuif), N. Idres was supported in
part by a studentship from the Ministère de l'Education Nationale de la Recherche et de la …

Cytochrome P450 (P450)-dependent metabolism of all-trans-retinoic acid (atRA) is important
for the expression of its biological activity. Because the human P450s involved in the …

We have shown that four metabolites of all-trans-retinoic acid (ATRA) (4-oxo-, 4-OH-, 18-OH-,
and 5,6-epoxy-RA) can induce maturation of NB4 promyelocytic leukemia cells (Idres, N., …

Protoporphyrin IX (Pp IX) silica nanoparticles, developed for effective use in photodynamic
therapy (PDT), were explored in in vitro and in vivo models with the ambition to improve …

Background Hafnium oxide, NBTXR3 nanoparticles were designed for high dose energy
deposition within cancer cells when exposed to ionizing radiation. The purpose of this study …

The cGAS-STING pathway can be activated by radiation induced DNA damage and because
of its important role in anti-cancer immunity activation, methods to increase its activation in …

Purpose Despite tremendous results achieved by immune checkpoint inhibitors, most
patients are not responders, mainly because of the lack of a pre-existing anti-tumor immune …

Purpose The side effects of radiotherapy induced on healthy tissue limit its use. To
overcome this issue and fully exploit the potential of radiotherapy to treat cancers, the first-in-class …

The purpose of this work was to identify the principal human cytochrome P450s (CYPs)
involved in the metabolism of the retinoic acid (RA) isomers, 9-cis- and 13-cis-RA, by using a …

… Marill J. So you say you want a redesign: usability, accessibility and the constraints of
designing a database-driven Website. Presented at: Library and Information Technology …