Small vessel disease is a disorder of cerebral microvessels that causes white matter
hyperintensities and several other common abnormalities (eg, recent small subcortical infarcts and …

Cerebral small vessel disease (SVD) is a common accompaniment of ageing. Features
seen on neuroimaging include recent small subcortical infarcts, lacunes, white matter …

The term cerebral small vessel disease (SVD) describes a range of neuroimaging, pathological,
and associated clinical features. Clinical features range from none, to discrete focal …

… EMBASE identified 3958 references, which included many additional publications to
trials that were already in the review, and several that were relevant to another review (Wardlaw …

Background Recombinant tissue plasminogen activator (rt-PA, alteplase) improved functional
outcome in patients treated soon after acute ischaemic stroke in randomised trials, but …

Methods A hybrid approach based on established processes described by Glaser15 and by
the National Institutes of Health (http://prevention. nih. gov/cdp/about. aspx) 16 was used to …

… Contributions by both Dr Farrall and Prof Wardlaw include study design, search strategy
development, data extraction and analysis, and manuscript drafting and editing. Dr Farrall …

Completely updated edition, written by a close-knit author team Presents a unique approach
to stroke-integrated clinical management that weaves together causation, presentation, …

The incidence of subarachnoid haemorrhage (SAH) is 6–8 per 100 000 person years, peaking
in the sixth decade. SAH, mostly due to rupture of an intracranial aneurysm, accounts for …

Age-associated disease and disability are placing a growing burden on society. However,
ageing does not affect people uniformly. Hence, markers of the underlying biological ageing …