Objective To determine the benefits and harms of subacromial decompression surgery in
adult patients with subacromial pain syndrome lasting for more than 3 months. Design …

Importance Nonspecific effects, particularly placebo effects, are thought to contribute
significantly to the observed effect in surgical trials. Objective To estimate the proportion of the …

Despite widespread endorsement, Teppo Järvinen and colleagues argue that evidence for
stratifying risk of fracture and subsequent drug therapy to prevent hip fracture is insufficient …

The continual innovation and proliferation of new research tools for the evaluation and
characterization of the skeleton has greatly broadened our understanding of bone physiology and …

Mediolateral three‐point bending of the rat midfemur was developed to enable the assessment
of the mechanical competence of the elliptic bone cross‐section in terms of its widest …

Although micro‐computed tomography (micro‐CT) has become the gold standard for
assessing the 3D structure of trabecular bone, its extension to cortical bone microstructure has …

Bone dynamically adapts its structure to the environmental demands placed upon it. Load-related
stimuli play an important role in this adaptation. It has been postulated that osteocytes …

Background According to prevailing understanding, skeletal mechano-responsiveness
declines with age and this apparent failure of the mechano-sensory feedback system has been …

… Jarkko Jokihaara, postdoctoral fellow5, … Cooper A, Nherera L, Calvert N, O’Flynn N,
Turnbull N, Robson J, et al. Clinical guidelines and evidence review for lipid modification …

Background The Numerical Rating Scale (NRS) and Patient-rated wrist/hand evaluation (PRWHE)
are patient-reported outcomes frequently used for evaluating pain and function of the …