[HTML][HTML] Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein
…, E Danielson, FAH Fonseca, J Genest… - New England journal …, 2008 - Mass Medical Soc
Background Increased levels of the inflammatory biomarker high-sensitivity C-reactive
protein predict cardiovascular events. Since statins lower levels of high-sensitivity C-reactive …
protein predict cardiovascular events. Since statins lower levels of high-sensitivity C-reactive …
The metabolic syndrome and cardiovascular risk: a systematic review and meta-analysis
S Mottillo, KB Filion, J Genest, L Joseph, L Pilote… - Journal of the American …, 2010 - jacc.org
Objectives : We sought to conduct a systematic review and meta-analysis of the cardiovascular
risk associated with the metabolic syndrome as defined by the 2001 National Cholesterol …
risk associated with the metabolic syndrome as defined by the 2001 National Cholesterol …
Homocyst (e) ine and cardiovascular disease: a critical review of the epidemiologic evidence
JW Eikelboom, E Lonn, J Genest Jr… - Annals of internal …, 1999 - acpjournals.org
Purpose: To review epidemiologic studies on the association between homocyst(e)ine level
and risk for cardiovascular disease and the potential benefits of homocysteine-decreasing …
and risk for cardiovascular disease and the potential benefits of homocysteine-decreasing …
[HTML][HTML] Antiinflammatory therapy with canakinumab for atherosclerotic disease
…, JH Cornel, P Pais, D Pella, J Genest… - New England journal …, 2017 - Mass Medical Soc
Background Experimental and clinical data suggest that reducing inflammation without
affecting lipid levels may reduce the risk of cardiovascular disease. Yet, the inflammatory …
affecting lipid levels may reduce the risk of cardiovascular disease. Yet, the inflammatory …
Mutations in ABC1 in Tangier disease and familial high-density lipoprotein deficiency
…, B Koop, S Pimstone, JJP Kastelein, J Genest… - Nature …, 1999 - nature.com
Genes have a major role in the control of high-density lipoprotein (HDL) cholesterol (HDL-C)
levels. Here we have identified two Tangier disease (TD) families, confirmed 9q31 linkage …
levels. Here we have identified two Tangier disease (TD) families, confirmed 9q31 linkage …
Reduction in C-reactive protein and LDL cholesterol and cardiovascular event rates after initiation of rosuvastatin: a prospective study of the JUPITER trial
PM Ridker, E Danielson, FAH Fonseca, J Genest… - The Lancet, 2009 - thelancet.com
Background Statins lower high-sensitivity C-reactive protein (hsCRP) and cholesterol
concentrations, and hypothesis generating analyses suggest that clinical outcomes improve in …
concentrations, and hypothesis generating analyses suggest that clinical outcomes improve in …
Effect of interleukin-1β inhibition with canakinumab on incident lung cancer in patients with atherosclerosis: exploratory results from a randomised, double-blind …
…, F Fonseca, J Nicolau, N Gotcheva, J Genest… - The Lancet, 2017 - thelancet.com
Background Inflammation in the tumour microenvironment mediated by interleukin 1β is
hypothesised to have a major role in cancer invasiveness, progression, and metastases. We did …
hypothesised to have a major role in cancer invasiveness, progression, and metastases. We did …
2009 Canadian Cardiovascular Society/Canadian guidelines for the diagnosis and treatment of dyslipidemia and prevention of cardiovascular disease in the adult …
J Genest, R McPherson, J Frohlich, T Anderson… - Canadian Journal of …, 2009 - Elsevier
… Genest et al Can J Cardiol Vol 25 No 10 October 2009 568 … McPherson R, Frohlich J,
Fodor G, Genest J; Canadian Cardiovascular Society. Canadian Cardiovascular Society …
Fodor G, Genest J; Canadian Cardiovascular Society. Canadian Cardiovascular Society …
2012 update of the Canadian Cardiovascular Society guidelines for the diagnosis and treatment of dyslipidemia for the prevention of cardiovascular disease in the …
Many developments have occurred since the publication of the widely-used 2009 Canadian
Cardiovascular Society (CCS) Dyslipidemia guidelines. Here, we present an updated …
Cardiovascular Society (CCS) Dyslipidemia guidelines. Here, we present an updated …
Familial lipoprotein disorders in patients with premature coronary artery disease.
JJ Genest Jr, SS Martin-Munley, JR McNamara… - Circulation, 1992 - Am Heart Assoc
BACKGROUND Genetic lipoprotein disorders have been associated with premature coronary
artery disease (CAD). METHODS AND RESULTS The prevalence of such disorders was …
artery disease (CAD). METHODS AND RESULTS The prevalence of such disorders was …