Two women with polycythemia vera and heterozygosity (Gd B /Gd A ) at the X-chromosomelinked
locus for glucose-6-phosphate dehydrogenase were studied to determine the nature of …

Angiotensin II exerts a mitogenic effect in several in vitro models, but a direct effect on erythroid
progenitors has not been documented. Angiotensin-converting enzyme inhibitors and …

OBJECTIVE: The somatic JAK2 V617F mutation is seen in most polycythemia vera (PV)
patients; however, it is not clear if JAK2 V617F is the PV-initiating mutation. METHODS: In order …

THE pluripotent haemopoietic stem cell has been the object of many investigations in murine
and human systems, but the origin of lymphoid cells from the human pluripotent stem cell …

… confirm the reported Epo independence, (b) sequencing of EPO cDNAs revealed no mutations,
and (c) the etiology of his polycythemic disorder remained unclear at that time (JT Prchal, …

… Prchal JT, Crist WM, Goldwasser E, Perrine G, Prchal JF: Autosomal dominant polycythemia.
Blood 66:1208, 1985 3. Prchal JT, Prchal JF: Evolving understanding of the cellular defect …

Familial and congenital polycythemia, not due to high oxygen affinity hemoglobin or reduced
2,3-diphosphoglycerate in erythrocytes, is common in the Chuvash population of the …

Primary polycythemias are caused by an acquired or inborn mutation affecting
hematopoietic/erythroid progenitors that results in an abnormal response to hematopoietic cytokines. …

Essential thrombocythemia (ET) and polycythemia vera (PV) are clonal myeloproliferative
disorders that are often difficult to distinguish from other causes of elevated blood cell counts. …

Serum vitamin B 12 levels (as determined by radio-immunoassay) were measured in 20
subjects aged 65 years and over with Alzheimer-type dementia, 20 age-matched subjects with …