Paediatricians and paediatric rheumatologists review a large number of children with ongoing
pain (disease and non-disease related). A small number of these develop chronic pain …

Background Antifibrinolytic agents are commonly used during cardiac surgery to minimize
bleeding and to reduce exposure to blood products. We sought to determine whether …

… Andrew Willan and Jennifer Clinch oversaw the analysis. Jennifer Clinch and Teresa
Janz conducted the analysis. Robert Glossop contributed to the development of the protocol, …

The classical criteria for the evaluation of clinical trials in cancer reflect alterations in
physical well-being, but are insensitive to other important factors, such as psychosocial state, …

We know little about the safety or efficacy of pharmacological medicines for children and
adolescents with chronic pain, despite their common use. Our aim was to conduct an overview …

Objective Euthanasia and physician-assisted suicide have become prominent medical and
social issues. This study investigated the prevalence of the desire for death in terminally ill …

Background Pain is a common feature of childhood and adolescence around the world, and
for many young people, that pain is chronic. The World Health Organization guidelines for …

In recent years, economists have been using socio-economic and socio-demographic
characteristics to explain self-reported individual happiness or satisfaction with life. Using …

Depression and anxiety disorders are thought to be common in palliative cancer care, but
there is inconsistent evidence regarding their relevance for other aspects of quality of life. In …

Adolescents with chronic pain also report severe disability and emotional distress. A clinical
sample of 80 adolescents and accompanying parents were investigated to first measure the …