p38 MAP kinases: key signalling molecules as therapeutic targets for inflammatory diseases
S Kumar, J Boehm, JC Lee - Nature reviews Drug discovery, 2003 - nature.com
… Lee, JC et al. A protein kinase involved in the regulation of inflammatory cytokine … &
Lee, JC p38 MAP kinase: molecular target for the inhibition of pro-inflammatory cytokines. …
Lee, JC p38 MAP kinase: molecular target for the inhibition of pro-inflammatory cytokines. …
EGFR Mutations in Lung Cancer: Correlation with Clinical Response to Gefitinib Therapy
JG Paez, PA Janne, JC Lee, S Tracy, H Greulich… - Science, 2004 - science.org
Receptor tyrosine kinase genes were sequenced in non–small cell lung cancer (NSCLC)
and matched normal tissue. Somatic mutations of the epidermal growth factor receptor gene …
and matched normal tissue. Somatic mutations of the epidermal growth factor receptor gene …
Staphylococcus aureus Capsular Polysaccharides
K O'Riordan, JC Lee - Clinical microbiology reviews, 2004 - Am Soc Microbiol
… CY Lee's laboratory sequenced the cap8 gene cluster, and the laboratories of TJ Foster and
JC Lee sequenced the cap5 gene cluster. The cap5 and cap8 loci are allelic and comprise …
JC Lee sequenced the cap5 gene cluster. The cap5 and cap8 loci are allelic and comprise …
Inhibition of p38 MAP kinase as a therapeutic strategy
JC Lee, S Kumar, DE Griswold, DC Underwood… - …, 2000 - Elsevier
Since the discovery of p38 MAP kinase in 1994, our understanding of its biology has progressed
dramatically. The key advances include (1) identification of p38 MAP kinase homologs …
dramatically. The key advances include (1) identification of p38 MAP kinase homologs …
Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease
Crohn’s disease and ulcerative colitis, the two common forms of inflammatory bowel disease
(IBD), affect over 2.5 million people of European ancestry, with rising prevalence in other …
(IBD), affect over 2.5 million people of European ancestry, with rising prevalence in other …
Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47
Genome-wide association studies and candidate gene studies in ulcerative colitis have
identified 18 susceptibility loci. We conducted a meta-analysis of six ulcerative colitis genome-…
identified 18 susceptibility loci. We conducted a meta-analysis of six ulcerative colitis genome-…
Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease
Genetic association studies have identified 215 risk loci for inflammatory bowel disease 1 ,
2 , 3 , 4 , 5 , 6 , 7 , 8 , thereby uncovering fundamental aspects of its molecular biology. We …
2 , 3 , 4 , 5 , 6 , 7 , 8 , thereby uncovering fundamental aspects of its molecular biology. We …
An oral SARS-CoV-2 Mpro inhibitor clinical candidate for the treatment of COVID-19
…, BL Hurst, EP Kadar, AS Kalgutkar, JC Lee, J Lee… - Science, 2021 - science.org
The worldwide outbreak of COVID-19 caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) has become a global pandemic. Alongside vaccines, antiviral …
coronavirus 2 (SARS-CoV-2) has become a global pandemic. Alongside vaccines, antiviral …
[HTML][HTML] Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study
Background Crohn's disease and ulcerative colitis are the two major forms of inflammatory
bowel disease; treatment strategies have historically been determined by this binary …
bowel disease; treatment strategies have historically been determined by this binary …
Measurements of Ω and Λ from 42 high-redshift supernovae
…, IM Hook, AG Kim, MY Kim, JC Lee… - The Astrophysical …, 1999 - iopscience.iop.org
We report measurements of the mass density, Ω $\mathstrut {_ {M}} $, and cosmological-constant
energy density, Ω $\mathstrut {_ {{\Lambda}}} $, of the universe based on the analysis …
energy density, Ω $\mathstrut {_ {{\Lambda}}} $, of the universe based on the analysis …