User profiles for I. Olivotto

iacopo olivotto

Cardiomyopathy Unit, Careggi University Hospital, Florence
Verified email at aou-careggi.toscana.it
Cited by 31703

[HTML][HTML] Long-term outcomes for neoadjuvant versus adjuvant chemotherapy in early breast cancer: meta-analysis of individual patient data from ten randomised trials

…, H Mukai, L Norton, Y Ohashi, I Olivotto… - The Lancet …, 2018 - thelancet.com
Background Neoadjuvant chemotherapy (NACT) for early breast cancer can make breast-conserving
surgery more feasible and might be more likely to eradicate micrometastatic …

Hypertrophic cardiomyopathy: present and future, with translation into contemporary cardiovascular medicine

…, SR Ommen, C Semsarian, P Spirito, I Olivotto… - Journal of the American …, 2014 - jacc.org
Hypertrophic cardiomyopathy (HCM) is a common inherited heart disease with diverse
phenotypic and genetic expression, clinical presentation, and natural history. HCM has been …

NF-κB signaling: multiple angles to target OA

KB Marcu, M Otero, E Olivotto, R Maria Borzi… - Current drug …, 2010 - ingentaconnect.com
In the context of OA disease, NF-κB transcription factors can be triggered by a host of stress-related
stimuli including pro-inflammatory cytokines, excessive mechanical stress and ECM …

[HTML][HTML] Effect of left ventricular outflow tract obstruction on clinical outcome in hypertrophic cardiomyopathy

MS Maron, I Olivotto, S Betocchi… - … England Journal of …, 2003 - Mass Medical Soc
Background The influence of left ventricular outflow tract obstruction on the clinical outcome
of hypertrophic cardiomyopathy remains unresolved. Methods We assessed the effect of …

[HTML][HTML] Adjuvant radiotherapy and chemotherapy in node-positive premenopausal women with breast cancer

…, M Paradis, AJ Coldman, IA Olivotto - … England Journal of …, 1997 - Mass Medical Soc
Background Radiotherapy after mastectomy to treat early breast cancer has been known
since the 1940s to reduce rates of local relapse. However, the routine use of postoperative …

Short-term clinical outcome of patients with acute pulmonary embolism, normal blood pressure, and echocardiographic right ventricular dysfunction

S Grifoni, I Olivotto, P Cecchini, F Pieralli, A Camaiti… - Circulation, 2000 - Am Heart Assoc
Background—The role of echocardiographic right ventricular (RV) dysfunction in predicting
clinical outcome in clinically stable patients with pulmonary embolism (PE) is undefined. In …

Mavacamten for treatment of symptomatic obstructive hypertrophic cardiomyopathy (EXPLORER-HCM): a randomised, double-blind, placebo-controlled, phase 3 trial

I Olivotto, A Oreziak, R Barriales-Villa, TP Abraham… - The Lancet, 2020 - thelancet.com
Background Cardiac muscle hypercontractility is a key pathophysiological abnormality in
hypertrophic cardiomyopathy, and a major determinant of dynamic left ventricular outflow tract (…

Hypertrophic cardiomyopathy is predominantly a disease of left ventricular outflow tract obstruction

MS Maron, I Olivotto, AG Zenovich, MS Link… - Circulation, 2006 - Am Heart Assoc
Background— Nonobstructive hypertrophic cardiomyopathy (HCM) has been regarded as
the predominant hemodynamic form of the disease on the basis of assessment of outflow …

[HTML][HTML] Regional nodal irradiation in early-stage breast cancer

TJ Whelan, IA Olivotto, WR Parulekar… - … England Journal of …, 2015 - Mass Medical Soc
Background Most women with breast cancer who undergo breast-conserving surgery receive
whole-breast irradiation. We examined whether the addition of regional nodal irradiation to …

Locoregional radiation therapy in patients with high-risk breast cancer receiving adjuvant chemotherapy: 20-year results of the British Columbia randomized trial

J Ragaz, IA Olivotto, JJ Spinelli… - Journal of the …, 2005 - academic.oup.com
Background: The British Columbia randomized radiation trial was designed to determine
the survival impact of locoregional radiation therapy in premenopausal patients with lymph …