Background The effect of a restrictive versus liberal red-cell transfusion strategy on clinical
outcomes in patients undergoing cardiac surgery remains unclear. Methods In this multicenter…

Background and Purpose— The importance of perioperative cognitive decline has long
been debated. We recently demonstrated a significant correlation between perioperative …

Background Delirium is a common and serious postoperative complication. Subanaesthetic
ketamine is often administered intraoperatively for postoperative analgesia, and some …

Background Cerebral oximetry is a noninvasive technology using near-infrared spectroscopy
(NIRS) to estimate regional cerebral oxygen saturation. Although NIRS cerebral oximetry is …

Millions of individuals with coronary artery or valvular heart disease have been given a new
chance at life by heart surgery, but the potential for neurological injury is an Achilles heel. …

Neurocognitive dysfunction is a common complication after cardiac surgery. We evaluated
in this prospective study the effect of rewarming rate on neurocognitive outcome after …

Background and Purpose— The absence of a widely available and sensitive diagnostic test
for acute cerebral ischemia remains a significant limitation in the diagnosis and …

Healthcare providers are facing a coronavirus disease pandemic. This pandemic may last
for many months, stressing the Canadian healthcare system in a way that has not previously …

Methods The initiative to identify the evidence base and develop findings for perfusion
practice evolved from conversations between 2 of the authors (KS, DR). Subsequent …

Objective: Although coronary artery bypass grafting (CABG) has been shown to improve quality
of life and functional capacity for many patients, recent studies have demonstrated that a …