Background. Knowledge of any harm associated with living kidney donation guides informed
consent and living donor follow-up. Risk estimates in the literature are variable, and most …

Importance Acute kidney injury (AKI) after pediatric cardiac surgery is associated with high
short-term morbidity and mortality; however, the long-term kidney outcomes are unclear. …

Importance Research has identified improved biomarkers of acute kidney injury (AKI). Cystatin
C (CysC) is a better glomerular filtration rate marker than serum creatinine (SCr) and may …

The use of novel biomarkers of acute kidney injury (AKI) in clinical trials may help evaluate
treatments for AKI. Here we explore potential applications of biomarkers in simulated clinical …

Deceased-donor acute kidney injury (AKI) is associated with organ discard and delayed graft
function, but data on longer-term allograft survival are limited. We performed a multicenter …

Background As children progress to higher stages of AKI, the risk for adverse outcomes
dramatically increases. No reliable methods exist to predict AKI progression in hospitalized …

Background Children undergoing cardiac surgery may exhibit a pronounced inflammatory
response to cardiopulmonary bypass (CPB). Inflammation is recognized as an important …

Background Inflammation is a key component of both acute kidney injury (AKI) and response
to cardiopulmonary bypass. Because AKI poses risks to children after cardiac surgery, we …

… stages of the work in collaboration with RX Liu and HR Thiessen-Philbrook. RX Liu and HR
Thiessen-Philbrook contributed significantly to data analysis and preparation of figures. All …

Importance The shortage of deceased donor kidneys for transplants is an ongoing concern.
Prior studies support transplanting kidneys from deceased donors with acute kidney injury (…