Objective To describe rates and risk factors for prolonged postoperative use of opioids in
patients who had not previously used opioids and undergoing major elective surgery. Design …

BACKGROUND: Neuropathic pain (NeP), redefined as pain caused by a lesion or a disease
of the somatosensory system, is a disabling condition that affects approximately two million …

BACKGROUND: Many clinical trials have demonstrated the effectiveness of gabapentin and
pregabalin administration in the perioperative period as an adjunct to reduce acute …

Background Functional capacity is an important component of risk assessment for major
surgery. Doctors' clinical subjective assessment of patients' functional capacity has uncertain …

Objective To systematically review the evidence of pre-operative exercise, known as ‘prehabilitation’,
on peri- and postoperative outcomes in adult surgical populations. Design …

The classic definition of preemptive analgesia requires 2 groups of patients to receive identical
treatment before or after incision or surgery. The only difference between the 2 groups is …

Background Total knee arthroplasty (TKA) is a common and costly surgical procedure.
Despite high success rates, many TKA patients develop chronic pain in the months and years …

Chronic postsurgical pain (CPSP), an often unanticipated result of necessary and even life-saving
procedures, develops in 5–10% of patients one-year after major surgery. Substantial …

Background Globally, medical cannabis legalization has increased in recent years and
medical cannabis is commonly used to treat chronic pain. However, there are few randomized …

Objective To provide family physicians with a practical clinical summary of the Canadian
Pain Society (CPS) revised consensus statement on the pharmacologic management of …