Inhibiting PD-L1 palmitoylation enhances T-cell immune responses against tumours
Checkpoint blockade therapy targeting the programmed-death ligand 1 (PD-L1) and its
receptor programmed cell death 1 promotes T-cell-mediated immunosurveillance against …
receptor programmed cell death 1 promotes T-cell-mediated immunosurveillance against …
[HTML][HTML] Cancer cell-intrinsic PD-1 and implications in combinatorial immunotherapy
H Yao, H Wang, C Li, JY Fang, J Xu - Frontiers in immunology, 2018 - frontiersin.org
Programmed death 1 (PD-1) and its two natural ligands PD-L1 and PD-L2 are responsible
for delivering inhibitory signals that regulate the balance between T cell activation, tolerance, …
for delivering inhibitory signals that regulate the balance between T cell activation, tolerance, …
HIP1R targets PD-L1 to lysosomal degradation to alter T cell–mediated cytotoxicity
Expression of programmed cell death 1 (PD-1) ligand 1 (PD-L1) protects tumor cells from T
cell–mediated immune surveillance, and immune checkpoint blockade (ICB) therapies …
cell–mediated immune surveillance, and immune checkpoint blockade (ICB) therapies …
Anterior cingulate cortex dysfunction underlies social deficits in Shank3 mutant mice
…, J Chen, Q Chen, K Ren, D Feng, H Mao, H Yao… - Nature …, 2019 - nature.com
Social deficit is a core clinical feature of autism spectrum disorder (ASD) but the underlying
neural mechanisms remain largely unclear. We demonstrate that structural and functional …
neural mechanisms remain largely unclear. We demonstrate that structural and functional …
Circular dichroism in functional quality evaluation of medicines
H Yao, E Wynendaele, X Xu, A Kosgei… - … of Pharmaceutical and …, 2018 - Elsevier
Circular dichroism (CD) is a non-destructive and powerful technique for providing structure
and ligand interaction information of small molecules as well as biotechnological medicines. …
and ligand interaction information of small molecules as well as biotechnological medicines. …
[HTML][HTML] Transversus abdominis plane block: an updated review of anatomy and techniques
…, TY Chuang, SF Yang, CC Chang, HY Yao… - BioMed research …, 2017 - hindawi.com
Purpose of Review. Transversus abdominis plane (TAP) block is a regional technique for
analgesia of the anterolateral abdominal wall. This review highlights the nomenclature system …
analgesia of the anterolateral abdominal wall. This review highlights the nomenclature system …
Skeletal muscle cell proliferation and differentiation on polypyrrole substrates doped with extracellular matrix components
KJ Gilmore, M Kita, Y Han, A Gelmi, MJ Higgins… - Biomaterials, 2009 - Elsevier
Conducting polymers have been developed as substrates for in vitro studies with a range of
cell types including electrically-excitable cells such as nerve and smooth muscle. The goal …
cell types including electrically-excitable cells such as nerve and smooth muscle. The goal …
[HTML][HTML] Regulation of PD-L1: emerging routes for targeting tumor immune evasion
Y Wang, H Wang, H Yao, C Li, JY Fang… - Frontiers in …, 2018 - frontiersin.org
Immune checkpoint blockade therapies (ICBTs) targeting programmed cell death 1 (PD-1)
and its ligand programmed death ligand-1 (PD-L1/B7-H1/CD274) have exhibited momentous …
and its ligand programmed death ligand-1 (PD-L1/B7-H1/CD274) have exhibited momentous …
[HTML][HTML] Engineering the heart: evaluation of conductive nanomaterials for improving implant integration and cardiac function
Recently, carbon nanotubes together with other types of conductive materials have been
used to enhance the viability and function of cardiomyocytes in vitro. Here we demonstrated a …
used to enhance the viability and function of cardiomyocytes in vitro. Here we demonstrated a …
Porous anorthite ceramics with ultra-low thermal conductivity
Y Han, C Li, C Bian, S Li, CA Wang - Journal of the European Ceramic …, 2013 - Elsevier
Porous anorthite ceramics with an ultra-low thermal conductivity of 0.018W/mK have been
fabricated by hydrous foam-gelcasting process and pressureless sintering method using γ-…
fabricated by hydrous foam-gelcasting process and pressureless sintering method using γ-…