The mental health effects of the coronavirus disease 2019 (COVID-19) pandemic might be
profound1 and there are suggestions that suicide rates will rise, although this is not inevitable. …

Suicide is a complex public health problem of global importance. Suicidal behaviour differs
between sexes, age groups, geographic regions, and sociopolitical settings, and variably …

Although recent years have seen large decreases in the overall global rate of suicide fatalities,
this trend is not reflected everywhere. Suicide and suicidal behaviour continue to present …

Maternal care influences hypothalamic-pituitary-adrenal (HPA) function in the rat through
epigenetic programming of glucocorticoid receptor expression. In humans, childhood abuse …

Background It is well known that most suicide cases meet criteria for a psychiatric disorder.
However, rates of specific disorders vary considerably between studies and little information …

Major depressive disorder (MDD) has an enormous impact on global disease burden, affecting
millions of people worldwide and ranking as a leading cause of disability for almost three …

Objective: Involvement of personality traits in susceptibility to suicidality has been the subject
of research since the 1950s. Because of the diversity of conceptual and methodological …

Restless legs syndrome (RLS) is a frequent neurological disorder characterized by an
imperative urge to move the legs during night, unpleasant sensation in the lower limbs, disturbed …

The early-life social environment can induce stable changes that influence neurodevelopment
and mental health. Research focused on early-life adversity revealed that early-life …

Although it is known that the methylation of DNA in 5′ promoters suppresses gene expression,
the role of DNA methylation in gene bodies is unclear 1 , 2 , 3 , 4 , 5 . In mammals, tissue…