A widespread decrease of mature microRNAs is often observed in human malignancies giving
them potential to act as tumor suppressors. Thus, microRNAs may be potential targets for …

Background: Many academic medical centres have introduced strategies to assess the
productivity of faculty as part of compensation schemes. We conducted a systematic review of the …

Neutrophils are the most abundant type of white blood cells circulating throughout the
bloodstream and are often considered the frontline defenders in innate immunity. However, …

Phosphorylation of p53 at Ser 46 was shown to regulate p53 apoptotic activity. Here we
demonstrate that homeodomain-interacting protein kinase-2 (HIPK2), a member of a novel …

This article investigates the mechanistic aspects of mutant p53 "gain of function" in
response to DNA damage. We show that mutant forms of p53 protein interact with NF-Y. The …

In mammals, molecular mechanisms and factors involved in the tight regulation of telomerase
expression and activity are still largely undefined. In this study, we provide evidence for a …

Background Safety and immunogenicity of BNT162b2 mRNA vaccine are unknown in
hematological patients; both were evaluated prospectively in 42 patients with multiple myeloma (…

Background Literature data suggests that age, gender and body mass index (BMI) could be
associated with difference in immune responses to vaccines. The first goal of the study was …

The overlapping histological and biochemical features underlying the beneficial effect of
deacetylase inhibitors and NO donors in dystrophic muscles suggest an unanticipated …

Expression of the Y-box protein YB-1 is increased in proliferating normal and cancer cells,
but its role in cell proliferation and cell cycle progression is unclear. We have identified a cell …