Purpose: To assess the effectiveness of azathioprine and 6-mercaptopurine in inducing
remission of active Crohn disease and the effectiveness of azathioprine in maintaining remission …

… Gordon H Fick is a senior biostatistician and settled discrepancies between Daniel J
Niven and Luc R Berthiaume during the review of the selected studies. Kevin B Laupland …

Introduction Severe acute renal failure (sARF) is associated with considerable morbidity,
mortality and use of healthcare resources; however, its precise epidemiology and long-term …

We conducted a prospective, observational cohort study designed to compare intestinal
permeability (IP) and development of multiple organ dysfunction syndrome (MODS) in a subset …

Background: People with low levels of vitamin D and its metabolites are at increased risk for
osteoporotic fractures. We wished to ascertain levels of vitamin D in a representative sample …

Objectives : This study sought to determine whether combined assessment of autonomic
tone plus cardiac electrical substrate identifies most patients at risk of serious events after …

Objective: To describe the incidence of non-neurologic organ dysfunction and its association
with outcome in patients with severe traumatic brain injury admitted to intensive care. …

Objective: To evaluate the serologic response to treatment of patients with infectious syphilis.
Design: Historical cohort study of all cases of infectious syphilis in Alberta from 1981 to …

Objectives: To determine whether supplementation with L-arginine reduces the incidence of
all stages of necrotizing enterocolitis (NEC) in premature infants with birth weight ≤1250 g …

Methods The University of Calgary Conjoint Health Research Ethics Board approved the
study protocol and all patients gave written, informed consent. Two hundred and thirteen …