* Studies involved elderly patients given the drug or placebo for 4–12 weeks. Although the
doses used in the trials were not indicated in the Dear Healthcare Professional Letter, they …

Reason for posting: Second-generation antipsychotic drugs, which are felt to have fewer
extrapyramidal adverse effects than the first-generation drugs, 1 are sometimes used to control …

Reason for posting: Sibutramine has been taken off the market in Italy after 50 adverse events
(primarily tachycardia, hypertension and arrhythmias) and 2 deaths from cardiovascular …

Reason for posting: Vitamin deficiency syndromes are uncommon in Western countries, but
many patients consume over-the-counter vitamin and mineral supplements with the hope of …

* Categories of specific antidepressants are mutually exclusive. Data were taken from a
GlaxoSmithKline report2 (available at http://ctr. gsk. co. uk/summary/paroxetine/epip083. pdf […

• Cardiovascular signs: raised jugular venous pressure, presence of third or fourth heart
sound, pericardial friction rub, muffled first heart sound, mitral or tricuspid regurgitation, …

Reason for posting: Palladone XL (hydromorphone hydrochloride) is a long-acting opioid
for chronic pain relief in patients with persistent, moderate-to-severe pain. A recent …

3. Gillespie IA, Adak GK, O’Brian SJ, et al. Milkborne general outbreaks of infectious intestinal
disease, England and Wales, 1992–2000. Epidemiol Infect 2003; 130: 461-8. 4. Statement …

Reason for posting: Health Canada warns that some over-the-counter supplements used to
increase energy and promote weight loss and bodybuilding pose a serious risk to health. 1 …

Reason for posting: Coxibs, the class of NSAIDs that selectively inhibit cyclooxygenase 2 (COX-2),
were designed to reduce joint pain and inflammation without causing the gastric …