Purpose: Recent studies have revealed that the majority of pediatric low-grade astrocytomas
(PLGA) harbor the BRAF-KIAA1549 (BK) fusion gene resulting in constitutive activation of …

OBJECTIVE: Cleft lip and/or palate (CLP) is the most common congenital craniofacial anomaly.
As a first step toward developing a quality of life (QOL) questionnaire for CLP patients, …

PURPOSE: The outcome of recurrent ependymoma in children is dismal. Reirradiation has
been proposed as an effective modality for ependymoma at relapse. However, the toxicity …

OBJECTIVE: To investigate school absenteeism among childhood cancer survivors and their
siblings and examine factors related to absenteeism in survivors. STUDY DESIGN: A cross-…

BACKGROUND: Patients with cleft lip and/or palate can undergo numerous procedures to
improve appearance, speech, dentition and hearing. We developed a cleft-specific patient-…

Introduction Patient-reported outcome (PRO) instruments should be developed according to
rigorous guidelines in order to provide clinically meaningful, scientifically sound …

Purpose In Canada, adolescent survivors of cancer are treated mainly at pediatric centers,
while young adults are treated at adult centers. Both care environments are reported as being …

Background Patient‐reported outcomes measures (PROMs) assess a patient’s subjective
appraisal of health outcomes from their own perspective. Despite hypothesised benefits that …

Objective: The goal of treatment for individuals with cleft lip and/or palate (CL/P) is to improve
physical, psychological, and social health. Outcomes of treatment are rarely measured …

Background: The CLEFT-Q is a new patient-reported outcome instrument designed to measure
outcomes that matter to patients. The aim of this qualitative study was to establish content …