Optical mapping of Langendorff-perfused human hearts: establishing a model for the study of ventricular fibrillation in humans

…, V Rao, S Mironov, E Sevaptsidis… - American Journal …, 2007 - journals.physiology.org
Our objective was to establish a novel model for the study of ventricular fibrillation (VF) in
humans. We adopted the established techniques of optical mapping to human ventricles for the …

Ventricular fibrillation in myopathic human hearts: mechanistic insights from in vivo global endocardial and epicardial mapping

…, E Downar, V Chauhan, E Sevaptsidis… - American Journal …, 2007 - journals.physiology.org
Ventricular fibrillation (VF) is an important cause of sudden cardiac death and cardiovascular
mortality in patients with cardiomyopathy. Although it was generally believed that chaotic …

[HTML][HTML] Ventricular tachycardia after surgical repair of tetralogy of Fallot: results of intraoperative mapping studies

…, L Mickleborough, W Williams, E Sevaptsidis… - Journal of the American …, 1992 - Elsevier
Objectives. Four patients with previous repair of tetralogy of Fallot and ventricular tachycardia
underwent map-guided surgery to ablate the arrhythmias. Background. Although patients …

Cardiac electrophysiological consequences of neuromuscular incapacitating device discharges

…, VS Chauhan, E Downar, E Sevaptsidis - Journal of the American …, 2006 - jacc.org
Objectives : The purpose of this study was to evaluate the cardiac consequences of
neuromuscular incapacitating device (NID)/stun gun discharge in an experimental model. …

[HTML][HTML] Endocardial mapping of ventricular tachycardia in the intact human heart. II. Evidence for multiuse reentry in a functional sheet of surviving myocardium

…, L Harris, L Mickleborough, E Sevaptsidis… - Journal of the American …, 1992 - Elsevier
Objective.The purpose of this study was to obtain improved detection and characterization of
reentrant circuits in the n-farcted human ventricle. Background. The return path of reentrant …

Cardiac stimulation with high voltage discharge from stun guns

…, S Massé, K Umapathy, P Dorian, E Sevaptsidis… - Cmaj, 2008 - Can Med Assoc
… D and E show magnified intracardiac electrograms of similar duration. It is evident in panel E
that … The morphology of the tachycardia in panel E is wider than the morphology in panel D. …

[HTML][HTML] Endocardial mapping of ventricular tachycardia in the intact human ventricle. III. Evidence of multiuse reentry with spontaneous and induced block in portions …

…, J Saito, JC Doig, TCK Chen, E Sevaptsidis… - Journal of the American …, 1995 - Elsevier
Objectives. This study was conducted to characterized the functional nature of the reentrant
tract responsible for ventricular tachycardia due to ischemic heart disease. Background. A …

Electrogram fractionation in murine HL-1 atrial monolayer model

…, M Husain, T Farid, E Downar, E Sevaptsidis… - Heart Rhythm, 2008 - Elsevier
BACKGROUND: Complex fractionated atrial electrograms have been suggested as important
targets for catheter ablation of atrial fibrillation. The etiology and the mechanism of these …

Effect of global ischemia and reperfusion during ventricular fibrillation in myopathic human hearts

…, J Asta, H Ross, V Rao, E Sevaptsidis… - American Journal …, 2009 - journals.physiology.org
The effect of lack of global coronary perfusion on myocardial activation rate, wavebreak, and
its temporal progression during human ventricular fibrillation (VF) is not known. We tested …

Spatiotemporal frequency analysis of ventricular fibrillation in explanted human hearts

K Umapathy, S Masse, E Sevaptsidis… - IEEE Transactions …, 2008 - ieeexplore.ieee.org
… [17] E. Sevaptsidis, “Simultaneous unipolar and bipolar recording of cardiac electrical … Elias
Sevaptsidis received the Graduate degree in instrumentation technology from Vanier College…