Regulation of neuronal PKA signaling through AKAP targeting dynamics

…, KE Smith, JA Gorski, EA Horne, ES Gibson… - European journal of cell …, 2006 - Elsevier
Central to organization of signaling pathways are scaffolding, anchoring and adaptor proteins
that mediate localized assembly of multi-protein complexes containing receptors, second …

Randomised clinical trial of strategies for improving medication compliance in primary hypertension

DL Sackett, ES Gibson, DW Taylor, RB Haynes… - The Lancet, 1975 - Elsevier
230 Canadian steelworkers with hyper-tension took part in a randomised trial to see if compliance
with antihypertensive drug regimens could be improved. For care and follow-up these …

Improvement of medication compliance in uncontrolled hypertension

RB Haynes, ES Gibson, BC Hackett, DL Sackett… - The Lancet, 1976 - Elsevier
38 hypertensive Canadian steelworkers who were neither compliant with medications nor at
goal diastolic blood-pressure six months after starting treatment were allocated either to a …

Can simple clinical measurements detect patient noncompliance?

RB Haynes, DW Taylor, DL Sackett, ES Gibson… - …, 1980 - Am Heart Assoc
Measurement of patient compliance is essential if management of low compliance is to be
performed efficiently. We assessed the value of several easily obtained clinical assessments …

Increased absenteeism from work after detection and labeling of hypertensive patients

…, DL Sackett, DW Taylor, ES Gibson… - … England Journal of …, 1978 - Mass Medical Soc
A study of hypertension in an industrial setting allowed us to confirm and explore an earlier
retrospective finding that the labeling of patients as hypertensive resulted in increased …

" Sleepiness" is serious in adolescence: Two surveys of 3235 Canadian students

ES Gibson, ACP Powles, L Thabane, S O'Brien… - BMC public health, 2006 - Springer
Background Evidence is growing that sleep problems in adolescents are significant
impediments to learning and negatively affect behaviour, attainment of social competence and …

Patient compliance with antihypertensive regimens

DL Sackett, RB Haynes, ES Gibson, DW Taylor… - Patient counselling and …, 1978 - Elsevier
Low compliance with antihypertensive drug regimens is a major cause of failure to achieve
adequate blood pressure control. A simple clinical interview can identify the noncompliant …

A light-triggered protein secretion system

D Chen, ES Gibson, MJ Kennedy - Journal of Cell Biology, 2013 - rupress.org
Optical control of protein interactions has emerged as a powerful experimental paradigm for
manipulating and studying various cellular processes. Tools are now available for …

AKAP150-anchored calcineurin regulates synaptic plasticity by limiting synaptic incorporation of Ca2+-permeable AMPA receptors

JL Sanderson, JA Gorski, ES Gibson… - Journal of …, 2012 - Soc Neuroscience
… We generated CaN anchoring-deficient AKAP150ΔPIX mice by homologous recombination
in ES … The resulting ES cells with the targeted akap5 ΔPIX allele were introduced into mouse …

Palmitoylation of A-kinase anchoring protein 79/150 regulates dendritic endosomal targeting and synaptic plasticity mechanisms

DJ Keith, JL Sanderson, ES Gibson… - Journal of …, 2012 - Soc Neuroscience
NMDA receptor-dependent long-term potentiation (LTP) and depression (LTD) are forms of
synaptic plasticity underlying learning and memory that are expressed through increases …