Regulation of neuronal PKA signaling through AKAP targeting dynamics
…, KE Smith, JA Gorski, EA Horne, ES Gibson… - European journal of cell …, 2006 - Elsevier
Central to organization of signaling pathways are scaffolding, anchoring and adaptor proteins
that mediate localized assembly of multi-protein complexes containing receptors, second …
that mediate localized assembly of multi-protein complexes containing receptors, second …
Randomised clinical trial of strategies for improving medication compliance in primary hypertension
230 Canadian steelworkers with hyper-tension took part in a randomised trial to see if compliance
with antihypertensive drug regimens could be improved. For care and follow-up these …
with antihypertensive drug regimens could be improved. For care and follow-up these …
Improvement of medication compliance in uncontrolled hypertension
RB Haynes, ES Gibson, BC Hackett, DL Sackett… - The Lancet, 1976 - Elsevier
38 hypertensive Canadian steelworkers who were neither compliant with medications nor at
goal diastolic blood-pressure six months after starting treatment were allocated either to a …
goal diastolic blood-pressure six months after starting treatment were allocated either to a …
Can simple clinical measurements detect patient noncompliance?
Measurement of patient compliance is essential if management of low compliance is to be
performed efficiently. We assessed the value of several easily obtained clinical assessments …
performed efficiently. We assessed the value of several easily obtained clinical assessments …
Increased absenteeism from work after detection and labeling of hypertensive patients
…, DL Sackett, DW Taylor, ES Gibson… - … England Journal of …, 1978 - Mass Medical Soc
A study of hypertension in an industrial setting allowed us to confirm and explore an earlier
retrospective finding that the labeling of patients as hypertensive resulted in increased …
retrospective finding that the labeling of patients as hypertensive resulted in increased …
" Sleepiness" is serious in adolescence: Two surveys of 3235 Canadian students
ES Gibson, ACP Powles, L Thabane, S O'Brien… - BMC public health, 2006 - Springer
Background Evidence is growing that sleep problems in adolescents are significant
impediments to learning and negatively affect behaviour, attainment of social competence and …
impediments to learning and negatively affect behaviour, attainment of social competence and …
Patient compliance with antihypertensive regimens
Low compliance with antihypertensive drug regimens is a major cause of failure to achieve
adequate blood pressure control. A simple clinical interview can identify the noncompliant …
adequate blood pressure control. A simple clinical interview can identify the noncompliant …
A light-triggered protein secretion system
D Chen, ES Gibson, MJ Kennedy - Journal of Cell Biology, 2013 - rupress.org
Optical control of protein interactions has emerged as a powerful experimental paradigm for
manipulating and studying various cellular processes. Tools are now available for …
manipulating and studying various cellular processes. Tools are now available for …
AKAP150-anchored calcineurin regulates synaptic plasticity by limiting synaptic incorporation of Ca2+-permeable AMPA receptors
JL Sanderson, JA Gorski, ES Gibson… - Journal of …, 2012 - Soc Neuroscience
… We generated CaN anchoring-deficient AKAP150ΔPIX mice by homologous recombination
in ES … The resulting ES cells with the targeted akap5 ΔPIX allele were introduced into mouse …
in ES … The resulting ES cells with the targeted akap5 ΔPIX allele were introduced into mouse …
Palmitoylation of A-kinase anchoring protein 79/150 regulates dendritic endosomal targeting and synaptic plasticity mechanisms
DJ Keith, JL Sanderson, ES Gibson… - Journal of …, 2012 - Soc Neuroscience
NMDA receptor-dependent long-term potentiation (LTP) and depression (LTD) are forms of
synaptic plasticity underlying learning and memory that are expressed through increases …
synaptic plasticity underlying learning and memory that are expressed through increases …