DURING the last two decades or so, there has been a struggle over the patient's role in medical
decision making that is often characterized as a conflict between autonomy and health, …

ContextAvailable data suggest that prospective research participants may frequently not
understand information disclosed to them in the informed consent process. Little is known about …

For more than three decades, interest in improving the care of dying patients has progressed
from being the concern of a few health-care professionals to being a widespread social …

Many believe that informed consent makes clinical research ethical. However, informed
consent is neither necessary nor sufficient for ethical clinical research. Drawing on the basic …

Allocating Scarce Medical Resources for Covid-19 The Covid-19 pandemic has already
stressed health care systems throughout the world, requiring rationing of medical equipment …

… Private companies spend enormous resources to amass high-quality, unbiased data to feed
their algorithms, and existing data in electronic health records (EHRs) or claims databases …

Background Cancer is the second leading cause of death in children, after accidents. Little is
known, however, about the symptoms and suffering at the end of life in children with cancer…

Background. Advance directives for medical care and the designation of proxy decision
makers to guide medical care after a patient has become incompetent have been widely …

accepted 2 September 2003; electronically published 17 February 2004. The views expressed
are those of the authors, reflecting their own personal research, and do not necessarily …

Allocation of very scarce medical interventions such as organs and vaccines is a persistent
ethical challenge. We evaluate eight simple allocation principles that can be classified into …