… Wells is the nominated principal investigator and Doug Coyle, Chris Cameron, and Karen
Lee are coinvestigators on the team grant. The publication of study results was not contingent …

Minimal research focuses on the process of decision making in the context of prenatal
screening and testing. This paper outlines an important contextual influence on these decisions. …

Objectives: The research objectives were two-fold: first, to systematically review the literature
on the cost-effectiveness of home telehealth for chronic diseases, and second to develop a …

Objectives For rare diseases it may be difficult to generate data from randomized trials to
support funding of a drug. Enzyme replacement therapies for diseases of inherited metabolic …

In this chapter, the focus is on the application of decision analytic tools to assist in reimbursement
decisions related to drugs for rare diseases. Focus is on the evaluative framework …

BACKGROUND: There is a dearth of information about the cost of allogenic red blood cells (RBCs)
and RBC transfusion in Canada in the aftermath of the Canadian blood system …

Background: The benefits of self-monitoring blood glucose levels are unclear in patients
with type 2 diabetes mellitus who do not use insulin, but there are considerable costs. We …

Background: The vital role played by family caregivers in supporting dying cancer patients
is well recognized, but the burden and economic impact on caregivers is poorly understood. …

Purpose Most women with breast cancer are diagnosed at an early stage and more than 80%
will be long-term survivors. Routine follow-up marks the transition from intensive treatment …

Background Serious infections are a major concern for patients considering treatments for
rheumatoid arthritis. Evidence is inconsistent as to whether biological drugs are associated …