Sst2, a Negative Regulator of Pheromone Signaling in the Yeast Saccharomyces cerevisiae: Expression, Localization, and Genetic Interaction and Physical …

HG Dohlman, J Song, D Ma… - … and cellular biology, 1996 - Taylor & Francis
Sst2 is the prototype for the newly recognized RGS (for regulators of G-protein signaling)
family. Cells lacking the pheromone-inducible SST2 gene product fail to resume growth after …

Alternative medicine: Herbal drugs and their critical appraisal-part II

…, M Gutiérrez-Rivas, L Menéndez-Arias, D Ma… - Progress in drug …, 2001 - Springer
The availability of herbal products as “over-the-counter” drugs and their increasing usage in
the US and Canada have caused concern at the US FDA, since these products are not …

Risk factors for early-onset group B streptococcal disease in neonates: a population-based case–control study

CE Adair, L Kowalsky, H Quon, D Ma, J Stoffman… - Cmaj, 2003 - Can Med Assoc
Background: Infection with group B streptococcus (GBS) is a major cause of neonatal illness
and death. We examined the antenatal and perinatal risk factors for early-onset GBS …

Discovery of cercosporamide, a known antifungal natural product, as a selective Pkc1 kinase inhibitor through high-throughput screening

…, JE Scott, JW Carpenter, MA Strege… - Eukaryotic …, 2004 - Am Soc Microbiol
The Pkc1-mediated cell wall integrity-signaling pathway is highly conserved in fungi and is
essential for fungal growth. We thus explored the potential of targeting the Pkc1 protein …

Antibodies to Capsular Polysaccharides of Group B Streptococcus in Pregnant Canadian Women: Relationship to Colonization Status and Infection in the Neonate

HD Davies, C Adair, A McGeer, D Ma… - The Journal of …, 2001 - academic.oup.com
In a cohort study of 1207 pregnant women in Alberta, Canada, the serotype distributions of
vaginal‐rectal group B Streptococcus (GBS) isolates were compared with all isolates from …

In vitro chemosensitivity of freshly explanted tumor cells to pemetrexed is correlated with target gene expression

…, S Hoffmann, H Hanauske-Abel, D Ma… - Investigational new …, 2007 - Springer
Aim of the study mRNA expression of genes involved in the mechanism of action of
pemetrexed was correlated with in vitro chemosensitivity of freshly explanted human tumor …

Virus population dynamics, fitness variations and the control of viral disease: an update

…, M Gutiérrez-Rivas, L Menéndez-Arias, D Ma… - Progress in drug …, 2001 - Springer
Viral quasispecies dynamics and variations of viral fitness are reviewed in connection with
viral disease control. Emphasis is put on resistance of human immunodeficiency virus and …

Perinatal antibiotic usage and changes in colonization and resistance rates of group B streptococcus and other pathogens

R Spaetgens, K DeBella, D Ma, S Robertson… - Obstetrics & …, 2002 - Elsevier
OBJECTIVE: To quantify current antibiotic usage during the perinatal period and impact on
vaginal-rectal colonizing organism resistance rates. METHODS: Swabs were obtained for …

Phosphorylation and localization of Kss1, a MAP kinase of the Saccharomyces cerevisiae pheromone response pathway.

D Ma, JG Cook, J Thorner - Molecular biology of the cell, 1995 - Am Soc Cell Biol
Kss1 protein kinase, and the homologous Fus3 kinase, are required for pheromone signal
transduction in Saccharomyces cerevisiae. In MATa haploids exposed to alpha-factor, Kss1 …

Applications of yeast in drug discovery

…, D Ma, CL Kaul, P Ramarao, JA Glasel, D Ma - Progress in drug …, 2001 - Springer
The yeast Saccharomyces cerevisiae is perhaps the best-studied eukaryotic organism. Its
experimental tractability, combined with the remarkable conservation of gene function …