Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes
COVID-19 and is spread person-to-person through close contact. We aimed to investigate the …

Background Oral immunotherapy is an emerging experimental treatment for peanut allergy,
but its benefits and harms are unclear. We systematically reviewed the efficacy and safety of …

Objective To compare the effects of treatments for coronavirus disease 2019 (covid-19).
Design Living systematic review and network meta-analysis. Data sources WHO covid-19 …

Concerns for anaphylaxis may hamper severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
immunization efforts. We convened a multidisciplinary group of international …

The selection of pharmacotherapy for patients with allergic rhinitis aims to control the disease
and depends on many factors. Grading of Recommendations Assessment, Development …

Severe asthma imposes a significant burden on patients, families and healthcare systems.
Management is difficult, due to disease heterogeneity, co‐morbidities, complexity in care …

Importance The benefits and harms of adding long-acting muscarinic antagonists (LAMAs) to
inhaled corticosteroids (ICS) and long-acting β 2 -agonists (LABAs) for moderate to severe …

Eosinophils natively inhabit the small intestine, but a functional role for them there has remained
elusive. Here, we show that eosinophil-deficient mice were protected from induction of …

Background Supplemental oxygen is often administered liberally to acutely ill adults, but the
credibility of the evidence for this practice is unclear. We systematically reviewed the …

Resolving conflict of interest The Joint Task Force on Practice Parameters (JTFPP) is
committed to ensuring that all guidelines are based on the best scientific evidence at the time of …