[HTML][HTML] Atrial fibrillation in patients with cryptogenic stroke
…, V Hachinski, SB Coutts, DJ Sahlas… - … England Journal of …, 2014 - Mass Medical Soc
Background Atrial fibrillation is a leading preventable cause of recurrent stroke for which
early detection and treatment are critical. However, paroxysmal atrial fibrillation is often …
early detection and treatment are critical. However, paroxysmal atrial fibrillation is often …
CT angiography “spot sign” predicts hematoma expansion in acute intracerebral hemorrhage
R Wada, RI Aviv, AJ Fox, DJ Sahlas, DJ Gladstone… - Stroke, 2007 - Am Heart Assoc
Background and Purpose— Morbidity and mortality in spontaneous intracerebral hemorrhage
(ICH) are correlated with hematoma progression. We hypothesized that the presence of …
(ICH) are correlated with hematoma progression. We hypothesized that the presence of …
Efficacy and safety of nerinetide for the treatment of acute ischaemic stroke (ESCAPE-NA1): a multicentre, double-blind, randomised controlled trial
…, D Roy, JL Rempel, ACR Rohr, D Iancu, DJ Sahlas… - The Lancet, 2020 - thelancet.com
Background Nerinetide, an eicosapeptide that interferes with post-synaptic density protein
95, is a neuroprotectant that is effective in preclinical stroke models of ischaemia-reperfusion. …
95, is a neuroprotectant that is effective in preclinical stroke models of ischaemia-reperfusion. …
Intravenous tenecteplase compared with alteplase for acute ischaemic stroke in Canada (AcT): a pragmatic, multicentre, open-label, registry-linked, randomised …
…, J Williams, J Brar, J Rivest, JZ Wang, J Dawe, J Stang… - The Lancet, 2022 - thelancet.com
Background Intravenous thrombolysis with alteplase bolus followed by infusion is a global
standard of care for patients with acute ischaemic stroke. We aimed to determine whether …
standard of care for patients with acute ischaemic stroke. We aimed to determine whether …
Perioperative covert stroke in patients undergoing non-cardiac surgery (NeuroVISION): a prospective cohort study
…, Q Ibrahim, SI Bangdiwala, S Yusuf, S Tsai, DJ Sahlas… - The Lancet, 2019 - thelancet.com
Background In non-surgical settings, covert stroke is more common than overt stroke and is
associated with cognitive decline. Although overt stroke occurs in less than 1% of adults after …
associated with cognitive decline. Although overt stroke occurs in less than 1% of adults after …
Canadian Stroke Best Practice Recommendations: Mood, Cognition and Fatigue following Stroke, 6th edition update 2019
…, MP Lindsay, EE Smith, DJ Sahlas… - … Journal of Stroke, 2020 - journals.sagepub.com
The 2019 update of the Canadian Stroke Best Practice Recommendations (CSBPR) for
Mood, Cognition and Fatigue following Stroke is a comprehensive set of evidence-based …
Mood, Cognition and Fatigue following Stroke is a comprehensive set of evidence-based …
A new visual rating scale to assess strategic white matter hyperintensities within cholinergic pathways in dementia
Background and Purpose— One possible mechanism of cognitive decline in individuals with
subcortical vascular disease is disruption of cholinergic fibers by ischemic lesions, such as …
subcortical vascular disease is disruption of cholinergic fibers by ischemic lesions, such as …
Strategic involvement of cholinergic pathways and executive dysfunction: Does location of white matter signal hyperintensities matter?
Cholinergic therapies have proven efficacious in the treatment of Alzheimer's disease, and
recently in vascular and mixed dementia. We set out to evaluate the impact of putative …
recently in vascular and mixed dementia. We set out to evaluate the impact of putative …
Prospective validation of the ABCD2 score for patients in the emergency department with transient ischemic attack
Background: The ABCD2 score (Age, Blood pressure, Clinical features, Duration of symptoms
and Diabetes) is used to identify patients having a transient ischemic attack who are at …
and Diabetes) is used to identify patients having a transient ischemic attack who are at …
Post-stroke depression, obstructive sleep apnea, and cognitive impairment: rationale for, and barriers to, routine screening
…, G Saposnik, Y Perez, DJ Sahlas… - … journal of stroke, 2016 - journals.sagepub.com
Stroke can cause neurological impairment ranging from mild to severe, but the impact of
stroke extends beyond the initial brain injury to include a complex interplay of devastating …
stroke extends beyond the initial brain injury to include a complex interplay of devastating …