[HTML][HTML] Atrial fibrillation in patients with cryptogenic stroke

…, V Hachinski, SB Coutts, DJ Sahlas… - … England Journal of …, 2014 - Mass Medical Soc
Background Atrial fibrillation is a leading preventable cause of recurrent stroke for which
early detection and treatment are critical. However, paroxysmal atrial fibrillation is often …

CT angiography “spot sign” predicts hematoma expansion in acute intracerebral hemorrhage

R Wada, RI Aviv, AJ Fox, DJ Sahlas, DJ Gladstone… - Stroke, 2007 - Am Heart Assoc
Background and Purpose— Morbidity and mortality in spontaneous intracerebral hemorrhage
(ICH) are correlated with hematoma progression. We hypothesized that the presence of …

Efficacy and safety of nerinetide for the treatment of acute ischaemic stroke (ESCAPE-NA1): a multicentre, double-blind, randomised controlled trial

…, D Roy, JL Rempel, ACR Rohr, D Iancu, DJ Sahlas… - The Lancet, 2020 - thelancet.com
Background Nerinetide, an eicosapeptide that interferes with post-synaptic density protein
95, is a neuroprotectant that is effective in preclinical stroke models of ischaemia-reperfusion. …

Intravenous tenecteplase compared with alteplase for acute ischaemic stroke in Canada (AcT): a pragmatic, multicentre, open-label, registry-linked, randomised …

…, J Williams, J Brar, J Rivest, JZ Wang, J Dawe, J Stang… - The Lancet, 2022 - thelancet.com
Background Intravenous thrombolysis with alteplase bolus followed by infusion is a global
standard of care for patients with acute ischaemic stroke. We aimed to determine whether …

Perioperative covert stroke in patients undergoing non-cardiac surgery (NeuroVISION): a prospective cohort study

…, Q Ibrahim, SI Bangdiwala, S Yusuf, S Tsai, DJ Sahlas… - The Lancet, 2019 - thelancet.com
Background In non-surgical settings, covert stroke is more common than overt stroke and is
associated with cognitive decline. Although overt stroke occurs in less than 1% of adults after …

Canadian Stroke Best Practice Recommendations: Mood, Cognition and Fatigue following Stroke, 6th edition update 2019

…, MP Lindsay, EE Smith, DJ Sahlas… - … Journal of Stroke, 2020 - journals.sagepub.com
The 2019 update of the Canadian Stroke Best Practice Recommendations (CSBPR) for
Mood, Cognition and Fatigue following Stroke is a comprehensive set of evidence-based …

A new visual rating scale to assess strategic white matter hyperintensities within cholinergic pathways in dementia

C Bocti, RH Swartz, FQ Gao, DJ Sahlas, P Behl… - Stroke, 2005 - Am Heart Assoc
Background and Purpose— One possible mechanism of cognitive decline in individuals with
subcortical vascular disease is disruption of cholinergic fibers by ischemic lesions, such as …

Strategic involvement of cholinergic pathways and executive dysfunction: Does location of white matter signal hyperintensities matter?

RH Swartz, DJ Sahlas, SE Black - Journal of Stroke and Cerebrovascular …, 2003 - Elsevier
Cholinergic therapies have proven efficacious in the treatment of Alzheimer's disease, and
recently in vascular and mixed dementia. We set out to evaluate the impact of putative …

Prospective validation of the ABCD2 score for patients in the emergency department with transient ischemic attack

…, M Émond, G Stotts, AY Jin, WJ Oczkowski, DJ Sahlas… - Cmaj, 2011 - Can Med Assoc
Background: The ABCD2 score (Age, Blood pressure, Clinical features, Duration of symptoms
and Diabetes) is used to identify patients having a transient ischemic attack who are at …

Post-stroke depression, obstructive sleep apnea, and cognitive impairment: rationale for, and barriers to, routine screening

…, G Saposnik, Y Perez, DJ Sahlas… - … journal of stroke, 2016 - journals.sagepub.com
Stroke can cause neurological impairment ranging from mild to severe, but the impact of
stroke extends beyond the initial brain injury to include a complex interplay of devastating …