Molecular basis of T cell inactivation by CTLA-4
CTLA-4, a negative regulator of T cell function, was found to associate with the T cell
receptor (TCR) complex ζ chain in primary T cells. The association of TCRζ with CTLA-4, …
receptor (TCR) complex ζ chain in primary T cells. The association of TCRζ with CTLA-4, …
Does culture matter? A cross-cultural study of executives' choice, decisiveness, and risk adjustment in international marketing
The authors investigate whether a manager's home culture significantly influences his or her
international marketing decisions. They also examine whether the impact of home culture …
international marketing decisions. They also examine whether the impact of home culture …
[PDF][PDF] The molecular taxonomy of primary prostate cancer
…, MS Lawrence, K Lau, T LeBien, D Lee, S Lee… - Cell, 2015 - cell.com
There is substantial heterogeneity among primary prostate cancers, evident in the spectrum
of molecular abnormalities and its variable clinical course. As part of The Cancer Genome …
of molecular abnormalities and its variable clinical course. As part of The Cancer Genome …
Guidelines for management of incidental pulmonary nodules detected on CT images: from the Fleischner Society 2017
The Fleischner Society Guidelines for management of solid nodules were published in 2005,
and separate guidelines for subsolid nodules were issued in 2013. Since then, new …
and separate guidelines for subsolid nodules were issued in 2013. Since then, new …
[HTML][HTML] Three-year overall survival with durvalumab after chemoradiotherapy in stage III NSCLC—update from PACIFIC
…, R Hui, T Kurata, A Chiappori, KH Lee… - Journal of Thoracic …, 2020 - Elsevier
Introduction In the phase 3 PACIFIC study of patients with unresectable stage III NSCLC
without progression after chemoradiotherapy, durvalumab demonstrated significant …
without progression after chemoradiotherapy, durvalumab demonstrated significant …
[HTML][HTML] A dynamic interplay between phytohormones is required for fruit development, maturation, and ripening
Plant species that bear fruit often utilize expansion of an ovary (carpel) or accessory tissue
as a vehicle for seed dispersal. While the seed(s) develop, the tissue(s) of the fruit follow a …
as a vehicle for seed dispersal. While the seed(s) develop, the tissue(s) of the fruit follow a …
Poly (ADP-ribose)(PAR) binding to apoptosis-inducing factor is critical for PAR polymerase-1–dependent cell death (parthanatos)
The mitochondrial protein apoptosis-inducing factor (AIF) plays a pivotal role in poly(ADP-ribose)
polymerase–1 (PARP-1)–mediated cell death (parthanatos), during which it is released …
polymerase–1 (PARP-1)–mediated cell death (parthanatos), during which it is released …
KMPI: measuring knowledge management performance
This paper provides a new metric, knowledge management performance index (KMPI), for
assessing the performance of a firm in its knowledge management (KM) at a point in time. …
assessing the performance of a firm in its knowledge management (KM) at a point in time. …
Mast cells: a cellular link between autoantibodies and inflammatory arthritis
DM Lee, DS Friend, MF Gurish, C Benoist, D Mathis… - Science, 2002 - science.org
… Our findings in the K/BxN model of destructive arthritis point to a likely role for mast cells
in human arthritis associated with immune complex formation, namely, cryoglobulin-associated …
in human arthritis associated with immune complex formation, namely, cryoglobulin-associated …
Do as i can, not as i say: Grounding language in robotic affordances
Large language models can encode a wealth of semantic knowledge about the world. Such
knowledge could be extremely useful to robots aiming to act upon high-level, temporally …
knowledge could be extremely useful to robots aiming to act upon high-level, temporally …