Rationale: Pulmonary nontuberculous mycobacterial (PNTM) disease is increasing, but
predisposing features have been elusive. Objectives: To prospectively determine the morphotype…

Infection is the second leading cause of death in patients with cancer. Loss of efficacy in
antibiotics due to antibiotic resistance in bacteria is an urgent threat against the continuing …

BACKGROUND: Impaired signaling in the IFN-γ/IL-12 pathway causes susceptibility to
severe disseminated infections with mycobacteria and dimorphic yeasts. Dominant gain-of-…

Adult stem cell transplantation (SCT) patients with graft-versus-host-disease (GVHD) exhibit
significant disruptions in gut microbial communities. These changes are associated with …

Klebsiella pneumoniae is the most clinically relevant species of this genus, known to cause
both community-acquired and nosocomial infections worldwide. In the past two decades, a …

The lack of effective and well-tolerated therapies against antibiotic-resistant bacteria is a
global public health problem leading to prolonged treatment and increased mortality. To …

A Gram-negative, aerobic, coccobacillus to rod-shaped bacterium was isolated from three
patients with chronic granulomatous disease. The organism was subjected to a polyphasic …

… These 2 peptides are some of the most effective in enabling penetration of PMOs in E. coli
[16… Studies using PPMOs have shown AcpP to be essential for growth of E. coli and S. enterica …

Background. Peptide-conjugated phosphorodiamidate morpholino oligomers (PPMOs) are
synthetic DNA/RNA analogues that silence expression of specific genes. We studied whether …

The intestinal inflammatory response of traveler's diarrhea acquired in Goa, India, and
Guadalajara, Mexico, was studied. Fecal lactoferrin was found in stool samples in which …