Physical function declines in old age, portending disability, increased health expenditures,
and mortality. Cellular senescence, leading to tissue dysfunction, may contribute to these …

<p id="p001">Forecasts of life expectancy are an important component of public policy that
influence age-based entitlement programs such as Social Security and Medicare. Although …

OBJECTIVE: The purpose of this study was to estimate and compare the effects of
antipsychotics—both the newer ones and the conventional ones—on body weight. METHOD: A …

ContextObesity is a major health problem in the United States, but the number of obesity-attributable
deaths has not been rigorously estimated.ObjectiveTo estimate the number of …

Context Public health officials and organizations have disseminated health messages
regarding the dangers of obesity, but these have not produced the desired effect. Objective To …

In just a few years, microarrays have gone from obscurity to being almost ubiquitous in
biological research. At the same time, the statistical methodology for microarray analysis has …

Caloric restriction (CR), without malnutrition, delays aging and extends life span in diverse
species; however, its effect on resistance to illness and mortality in primates has not been …

OBJECTIVE: To describe and provide estimates of the distribution of waist circumference (WC)
according to percentiles in African-, European-, and Mexican-American children, and to …

Obesity is an important risk factor for cardiometabolic diseases, including diabetes,
hypertension, dyslipidemia, and coronary heart disease (CHD). Several leading national and …

Objectives: To test the hypothesis that in a healthy pediatric population body mass index as (BMI)
(kilograms per meter square) is a valid measure of fatness that is independent of age …