User profiles for Daryl J. Wile
 | Daryl WileNeurology Verified email at mail.ubc.ca Cited by 1284 |
Association of metformin, elevated homocysteine, and methylmalonic acid levels and clinically worsened diabetic peripheral neuropathy
DJ Wile, C Toth - Diabetes care, 2010 - Am Diabetes Assoc
OBJECTIVE The severity of peripheral neuropathy in diabetic patients varies for unclear
reasons. Long-term use of metformin is associated with malabsorption of vitamin B 12 (…
reasons. Long-term use of metformin is associated with malabsorption of vitamin B 12 (…
Smart watch accelerometry for analysis and diagnosis of tremor
DJ Wile, R Ranawaya, ZHT Kiss - Journal of neuroscience methods, 2014 - Elsevier
Background Distinguishing the postural re-emergent tremor of Parkinson disease from
essential tremor can be difficult clinically. Use of accelerometry to aid diagnosis is limited to …
essential tremor can be difficult clinically. Use of accelerometry to aid diagnosis is limited to …
Serotonin and dopamine transporter PET changes in the premotor phase of LRRK2 parkinsonism: cross-sectional studies
DJ Wile, PA Agarwal, M Schulzer, E Mak… - The Lancet …, 2017 - thelancet.com
Background People with Parkinson's disease can show premotor neurochemical changes
in the dopaminergic and non-dopaminergic systems. Using PET, we assessed whether …
in the dopaminergic and non-dopaminergic systems. Using PET, we assessed whether …
The effect of LRRK2 mutations on the cholinergic system in manifest and premanifest stages of Parkinson's disease: a cross-sectional PET study
Background Markers of neuroinflammation are increased in some patients with LRRK2
Parkinson's disease compared with individuals with idiopathic Parkinson's disease, suggesting …
Parkinson's disease compared with individuals with idiopathic Parkinson's disease, suggesting …
Behavior therapy for Tourette syndrome: a systematic review and meta-analysis
DJ Wile, TM Pringsheim - Current treatment options in neurology, 2013 - Springer
Opinion statement When tics caused by Tourette Syndrome cause meaningful impairment
for patients, a comprehensive treatment approach includes education of patients, peers, and …
for patients, a comprehensive treatment approach includes education of patients, peers, and …
[HTML][HTML] Short term effects of contralateral tendon vibration on motor unit discharge rate variability and force steadiness in people with Parkinson's disease
C Kim, DJ Wile, SN Kraeutner, KA Larocque… - Frontiers in Aging …, 2024 - frontiersin.org
Background Vibration of one limb affects motor performance of the contralateral limb, and
this may have clinical implications for people with lateralized motor impairments through …
this may have clinical implications for people with lateralized motor impairments through …
A scan without evidence is not evidence of absence: Scans without evidence of dopaminergic deficit in a symptomatic leucine‐rich repeat kinase 2 mutation carrier
DJ Wile, K Dinelle, N Vafai, J McKenzie… - Movement …, 2016 - Wiley Online Library
Introduction The basis for SWEDD is unclear, with most cases representing PD mimics but
some later developing PD with a dopaminergic deficit. Methods We studied a patient initially …
some later developing PD with a dopaminergic deficit. Methods We studied a patient initially …
[HTML][HTML] Importance of maximal strength and muscle-tendon mechanics for improving force steadiness in persons with parkinson's disease
Although plantar flexion force steadiness (FS) is reduced in persons with Parkinson’s disease
(PD), the underlying causes are unknown. The aim of this exploratory design study was to …
(PD), the underlying causes are unknown. The aim of this exploratory design study was to …
[HTML][HTML] Intermuscular coherence of plantar and dorsiflexor muscles in older adults with Parkinson's disease and age-matched controls during bipedal and unipedal …
Introduction Postural instability increases with age and is exacerbated in neurological
disorders such as Parkinson’s disease (PD). Reducing the base of support from bipedal to …
disorders such as Parkinson’s disease (PD). Reducing the base of support from bipedal to …
[HTML][HTML] Serotonin transporter binding and motor onset of Parkinson's disease in asymptomatic LRRK2 mutation carriers: a cross-sectional study
DJ Wile, PA Agarwal, M Schulzer, E Mak… - The Lancet …, 2017 - ncbi.nlm.nih.gov
Background Patients with Parkinson’s Disease (PD) may exhibit premotor neurochemical
changes in dopaminergic (DA) and nondopaminergic systems. Using positron emission …
changes in dopaminergic (DA) and nondopaminergic systems. Using positron emission …