There are many potential barriers to the effective delivery of a drug in its active form to solid
tumors. Most small-molecule chemotherapeutic agents have a large volume of distribution on …

▪ Abstract Acetylation is a key posttranslational modification of many proteins responsible for
regulating critical intracellular pathways. Although histones are the most thoroughly studied …

This paper reviews the principal theoretical models of drug craving and provides some
directions for future research. The main models are classified broadly into three categories: (1) …

We describe evidence for a novel mechanism of monoclonal antibody (MAb)–directed
nanoparticle (immunoliposome) targeting to solid tumors in vivo. Long-circulating …

… This figure was reproduced with permission from Drummond, DC PhD thesis, Indiana … an
effect at the 1 h time point (Drummond and Daleke, unpublished observations). This problem …

We hypothesized that immunoliposomes (ILs) that target epidermal growth factor receptor (EGFR)
and/or its truncated variant EGFRvIII can be constructed to provide efficient …

We previously reported the development of epidermal growth factor receptor (EGFR)–targeted
immunoliposomes that bind and internalize in tumor cells which overexpress EGFR and/…

Liposome formulations of camptothecins have been actively pursued because of the potential
for significant pharmacologic advantages from successful drug delivery of this important …

This paper examines the application of the cue‐reactivity paradigm as a means of studying
alcohol dependence in clinical populations. Three main areas of application will be examined…

… Colin Drummond]). Each subject had the same therapist throughout treatment, and both
therapists administered both treatments to approximately the same number of subjects in each …