ContextSymptoms suggestive of acute urinary tract infection (UTI) constitute one of the most
common reasons for women to visit clinicians. Although the clinical encounter typically …

… Simel DL, Bossuyt PM. Differences between univariate and bivariate models for …
Disclaimer: Dr Simel had no role in the peer review of or the editorial decision to accept this …

… in the Rational Clinical Examination series, adapted from Holleman and Simel 26 as shown
below: … Disclaimer: Dr Simel was not involved in the editorial evaluation or decision making …

Confidence intervals are important summary measures that provide useful information from
clinical investigations, especially when comparing data from different populations or sites. …

ObjectiveTo review, systematically, the physical diagnosis of hypovolemia in adults.MethodsWe
searched MEDLINE (January 1966-November 1997), personal files, and bibliographies …

… As demonstrated by Holleman and Simel, 36 violation of the conditional independence
assumption can yield inaccurate posttest probabilities of disease. Unfortunately, the precision …

Objective To extend the validity of the Shoulder Pain and Disability Index (SPADI) by (1)
making it suitable for telephone administration;(2) determining its convergent validity with other …

… Farkouh ME, Oddone EZ, Simel DL. Improving the clinical examination for a low ankle-…
Disclaimer: Dr Simel did not participate in the peer review or editorial decision to accept this …

ContextWhile most meniscal or ligamentous knee injuries heal with nonoperative treatments,
a subset should be treated with arthroscopic or open surgery.ObjectiveTo analyze the …

Importance Obstructive sleep apnea is a common disease, responsible for daytime sleepiness.
Prior to referring patients for definitive testing, the likelihood of obstructive sleep apnea …