TH17-associated cytokines (IL-17A and IL-17F) in severe asthma
…, JG Martin, R Olivenstein, C Lemière… - Journal of Allergy and …, 2009 - jacionline.org
* These authors contributed equally to this project. Supported by grants from the National
Institutes of Health (AI026322, HL63248, and AI066020) and an award from the Bunning Food …
Institutes of Health (AI026322, HL63248, and AI066020) and an award from the Bunning Food …
Increased expression of IL-33 in severe asthma: evidence of expression by airway smooth muscle cells
…, R Olivenstein, AJ Halayko, C Lemiere… - The Journal of …, 2009 - journals.aai.org
IL-33, a new member of the IL-1 cytokine family, promotes Th2 inflammation, but evidence
on the implications of this cytokine in asthma is lacking. IL-33 would be mainly expressed by …
on the implications of this cytokine in asthma is lacking. IL-33 would be mainly expressed by …
Diagnosis and management of work-related asthma: American College of Chest Physicians Consensus Statement
…, CT Cowl, F Daroowalla, P Harber, C Lemiere… - Chest, 2008 - Elsevier
Background A previous American College of Chest Physicians Consensus Statement on
asthma in the workplace was published in 1995. The current Consensus Statement updates the …
asthma in the workplace was published in 1995. The current Consensus Statement updates the …
Overdiagnosis of asthma in obese and nonobese adults
…, RA McIvor, JM FitzGerald, P Hernandez, C Lemiere… - Cmaj, 2008 - Can Med Assoc
Background: It is unclear whether asthma is overdiagnosed in developed countries, particularly
among obese individuals, who may be more likely than nonobese people to experience …
among obese individuals, who may be more likely than nonobese people to experience …
Increased numbers of activated group 2 innate lymphoid cells in the airways of patients with severe asthma and persistent airway eosinophilia
…, GM Gauvreau, LP Boulet, C Lemiere… - Journal of Allergy and …, 2016 - Elsevier
Background In patients with severe eosinophilic asthma, local maturation rather than systemic
recruitment of mature cells might contribute to persistent airway eosinophilia. Group 2 …
recruitment of mature cells might contribute to persistent airway eosinophilia. Group 2 …
Reevaluation of diagnosis in adults with physician-diagnosed asthma
…, JM FitzGerald, M Ainslie, S Gupta, C Lemière… - Jama, 2017 - jamanetwork.com
Importance Although asthma is a chronic disease, the expected rate of spontaneous
remissions of adult asthma and the stability of diagnosis are unknown. Objective To determine …
remissions of adult asthma and the stability of diagnosis are unknown. Objective To determine …
[HTML][HTML] Reslizumab for inadequately controlled asthma with elevated blood eosinophil levels: a randomized phase 3 study
L Bjermer, C Lemiere, J Maspero, S Weiss, J Zangrilli… - Chest, 2016 - Elsevier
Background This phase 3 study further characterizes the efficacy and safety of reslizumab (a
humanized anti-IL-5 monoclonal antibody) in patients aged 12 to 75 years with asthma …
humanized anti-IL-5 monoclonal antibody) in patients aged 12 to 75 years with asthma …
Differences in airway remodeling between subjects with severe and moderate asthma
C Pepe, S Foley, J Shannon, C Lemiere… - Journal of Allergy and …, 2005 - Elsevier
BACKGROUND: Airway remodeling in asthma comprises a range of structural changes.
Several studies have suggested an association between these changes and disease severity. …
Several studies have suggested an association between these changes and disease severity. …
Occupational asthma
SM Tarlo, C Lemiere - New England Journal of Medicine, 2014 - Mass Medical Soc
Occupational asthma has been defined as asthma due to conditions attributable to work
exposures, not to causes outside the workplace. This review focuses on current data on …
exposures, not to causes outside the workplace. This review focuses on current data on …
Canadian Thoracic Society 2012 guideline update: diagnosis and management of asthma in preschoolers, children and adults
MD Lougheed, C Lemiere, FM Ducharme… - Canadian respiratory …, 2012 - hindawi.com
BACKGROUND: In 2010, the Canadian Thoracic Society (CTS) published a Consensus
Summary for the diagnosis and management of asthma in children six years of age and older, …
Summary for the diagnosis and management of asthma in children six years of age and older, …