[HTML][HTML] Extension of human cell lifespan by nicotinamide phosphoribosyltransferase
E van der Veer, C Ho, C O'Neil, N Barbosa… - Journal of Biological …, 2007 - ASBMB
Extending the productive lifespan of human cells could have major implications for diseases
of aging, such as atherosclerosis. We identified a relationship between aging of human …
of aging, such as atherosclerosis. We identified a relationship between aging of human …
Pre–B-Cell Colony–Enhancing Factor Regulates NAD+-Dependent Protein Deacetylase Activity and Promotes Vascular Smooth Muscle Cell Maturation
E van der Veer, Z Nong, C O'Neil, B Urquhart… - Circulation …, 2005 - Am Heart Assoc
Conversion of vascular smooth muscle cells (SMCs) from a proliferative state to a
nonproliferative, contractile state confers vasomotor function to developing and remodeling blood …
nonproliferative, contractile state confers vasomotor function to developing and remodeling blood …
The preventability of ventilator-associated events. The CDC prevention epicenters wake up and breathe collaborative
…, J Jernigan, S Magill, R Lyles, C O'Neil… - American journal of …, 2015 - atsjournals.org
Rationale: The CDC introduced ventilator-associated event (VAE) definitions in January
2013. Little is known about VAE prevention. We hypothesized that daily, coordinated …
2013. Little is known about VAE prevention. We hypothesized that daily, coordinated …
Association of inappropriate outpatient pediatric antibiotic prescriptions with adverse drug events and health care expenditures
…, JM Sahrmann, KB Nickel, CA O'Neil… - JAMA network …, 2022 - jamanetwork.com
Importance Nonguideline antibiotic prescribing for the treatment of pediatric infections is
common, but the consequences of inappropriate antibiotics are not well described. Objective To …
common, but the consequences of inappropriate antibiotics are not well described. Objective To …
[HTML][HTML] Regulation of macrophage cholesterol efflux through hydroxymethylglutaryl-CoA reductase inhibition: a role for RhoA in ABCA1-mediated cholesterol efflux
…, JY Edwards, CG Sawyez, CH O'Neil… - Journal of Biological …, 2005 - ASBMB
The cholesterol biosynthetic pathway produces numerous signaling molecules. Oxysterols
through liver X receptor (LXR) activation regulate cholesterol efflux, whereas the non-sterol …
through liver X receptor (LXR) activation regulate cholesterol efflux, whereas the non-sterol …
Fibroblast growth factor 9 delivery during angiogenesis produces durable, vasoresponsive microvessels wrapped by smooth muscle cells
…, M Drangova, C O'neil, MN Rahman, O Akawi… - Nature …, 2011 - nature.com
The therapeutic potential of angiogenic growth factors has not been realized. This may be
because formation of endothelial sprouts is not followed by their muscularization into …
because formation of endothelial sprouts is not followed by their muscularization into …
Characterization of aerosols generated during patient care activities
Background Questions remain about the degree to which aerosols are generated during
routine patient care activities and whether such aerosols could transmit viable pathogens to …
routine patient care activities and whether such aerosols could transmit viable pathogens to …
Four-dimensional microvascular analysis reveals that regenerative angiogenesis in ischemic muscle produces a flawed microcirculation
…, N Ghonaim, S Milkovich, B Balint, C O'Neil… - Circulation …, 2017 - Am Heart Assoc
Rationale: Angiogenesis occurs after ischemic injury to skeletal muscle, and enhancing this
response has been a therapeutic goal. However, to appropriately deliver oxygen, a precisely …
response has been a therapeutic goal. However, to appropriately deliver oxygen, a precisely …
A central line care maintenance bundle for the prevention of central line–associated bloodstream infection in non–intensive care unit settings
C O'Neil, K Ball, H Wood, K McMullen… - Infection control & …, 2016 - cambridge.org
OBJECTIVETo evaluate a central line care maintenance bundle to reduce central line–associated
bloodstream infection (CLABSI) in non–intensive care unit settings.DESIGNBefore-…
bloodstream infection (CLABSI) in non–intensive care unit settings.DESIGNBefore-…
Comparing the performance of 3 bioaerosol samplers for influenza virus
Respiratory viral diseases can be spread when a virus-containing particle (droplet) from one
individual is aerosolized and subsequently comes into either direct or indirect contact with …
individual is aerosolized and subsequently comes into either direct or indirect contact with …
